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Levothyroxine, also known as L-thyroxine, is a synthetic form of the thyroid hormone thyroxine (T 4). [5] [8] It is used to treat thyroid hormone deficiency (hypothyroidism), including a severe form known as myxedema coma. [5]
Physicians are cautioned to avoid switching patients from branded to generic, or between different generic manufacturers, when prescribing anti-epileptic drugs, warfarin, and levothyroxine. [ 11 ] Major issues were raised in the verification of bioequivalence when multiple generic versions of FDA-approved generic drug were found not to be ...
Thyroxine, also known as T 4, is a hormone produced by the thyroid gland.It is the primary form of thyroid hormone found in the blood and acts as a prohormone of the more active thyroid hormone, triiodothyronine (T 3). [1]
Brand names and generic names are differentiated by capitalizing brand names. See also the list of the top 100 bestselling branded drugs, ranked by sales. Abbreviations are used in the list as follows: INN = International Nonproprietary Name; BAN = British Approved Name; USAN = United States Adopted Name; Two-letter codes for countries
All of the drugs cost less than $15 for a month's prescription and are also available as generics.
[15] [16] [17] Different polymorphs of the compound have different solubilities and potencies. [18] Additionally, natural thyroid hormone supplements from the dried thyroids of animals are still available. [17] [19] [20] Levothyroxine contains T 4 only and is therefore largely ineffective for patients unable to convert T 4 to T 3. [21]
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Liotrix is a 4:1 mixture of thyroxine (T 4) and triiodothyronine (T 3) made synthetically.It is used to replenish thyroid hormones in thyroid deficiency and hypothyroidism.The only brand of liotrix available in the U.S. is Thyrolar, manufactured by Forest Laboratories.