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Subacute sclerosing panencephalitis (SSPE), also known as Dawson disease, is a rare form of progressive brain inflammation caused by a persistent infection with the measles virus. The condition primarily affects children, teens, and young adults. It has been estimated that about 2 in 10,000 people who get measles will eventually develop SSPE. [1]
The virus causes measles, a highly contagious disease transmitted by respiratory aerosols that triggers a temporary but severe immunosuppression.Symptoms include fever, cough, runny nose, inflamed eyes and a generalized, maculopapular, erythematous rash and a pathognomonic Koplik spot seen on buccal mucosa opposite to lower 1st and 2nd molars.
[3] [5] [12] [13] [14] Other names include morbilli, rubeola, red measles, and English measles. [1] [2] Both rubella, also known as German measles, and roseola are different diseases caused by unrelated viruses. [15] Symptoms usually develop 10–12 days after exposure to an infected person and last 7–10 days.
The information obtained in this way, together with the physical examination, enables the physician and other health professionals to form a diagnosis and treatment plan. If a diagnosis cannot be made, a provisional diagnosis may be formulated, and other possibilities (the differential diagnoses ) may be added, listed in order of likelihood by ...
The term morbilliform refers to a rash that looks like measles. [ 1 ] [ 2 ] The rash consists of macular lesions that are red and usually 2–10 mm in diameter but may be confluent in places. [ 3 ] A morbilliform rash is a rose-red flat ( macular ) or slightly elevated ( maculopapular ) eruption, showing circular or elliptical lesions varying ...
Koplik's spots are named after Henry Koplik (1858–1927), an American pediatrician who published a short description of them in 1896, emphasising their appearance before the skin rash and their value in the differential diagnosis of diseases with which measles might be mistaken.
This page was last edited on 20 September 2024, at 02:09 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.
In a physical examination, medical examination, clinical examination, or medical checkup, a medical practitioner examines a patient for any possible medical signs or symptoms of a medical condition. It generally consists of a series of questions about the patient's medical history followed by an examination based on the reported symptoms.