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The synergy between trimethoprim and sulfamethoxazole was first described in the late 1960s. [25] [26] [27] Trimethoprim and sulfamethoxazole have a greater effect when given together than when given separately, because they inhibit successive steps in the folate synthesis pathway. They are given in a one-to-five ratio in their tablet ...
Plazomicin is approved by the U.S. Food and Drug Administration (FDA) for adults with complicated urinary tract infections, including pyelonephritis, caused by Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, or Enterobacter cloacae, in patients who have limited or no alternative treatment options.
Effective treatment against all stages of the disease may require a combination of medications. [2] Infections without symptoms may be treated with just one antibiotic, and infections with symptoms are treated with two antibiotics. [3] Amoebiasis is present all over the world, [6] though most cases occur in the developing world. [7]
New CDC guidance advises taking a common antibiotic within 72 hours after unprotected sexual activity to prevent the spread of sexually transmitted infections (STIs). These new recommendations ...
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Narrow-spectrum antibiotics have low propensity to induce bacterial resistance and are less likely to disrupt the microbiome (normal microflora). [3] On the other hand, indiscriminate use of broad-spectrum antibiotics may not only induce the development of bacterial resistance and promote the emergency of multidrug-resistant organisms, but also cause off-target effects due to dysbiosis.
The CDC is proposing that health providers offer a single 200-milligram dose of doxycycline to gay and bisexual men who have sex with… CDC proposes antibiotic as morning-after STI treatment for ...
Clarithromycin was invented by researchers at the Japanese drug company Taisho Pharmaceutical in 1980. [5] The product emerged through efforts to develop a version of the antibiotic erythromycin that did not experience acid instability in the digestive tract, causing side effects, such as nausea and stomachache. Taisho filed for patent ...
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