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The Vaccine Adverse Event Reporting System (VAERS) is a United States program for vaccine safety, co-managed by the U.S. Centers for Disease Control and Prevention (CDC) and the Food and Drug Administration (FDA). [1]
In December 2021, following a request from the CEO of Delta Air Lines, CDC shortened its recommended isolation period for asymptomatic individuals infected with COVID-19 from 10 days to five. [122] [123] [124] Until 2022, the CDC withheld critical data about COVID-19 vaccine boosters, hospitalizations and wastewater data. [125]
COVID-19 vaccine clinical research uses clinical research to establish the characteristics of COVID-19 vaccines. These characteristics include efficacy , effectiveness , and safety. As of November 2022 [update] , 40 vaccines are authorized by at least one national regulatory authority for public use: [ 1 ] [ 2 ]
Countries should report on a case-by-case basis as far as possible but, in case of limitation in resources, aggregate weekly reporting is also possible. [2] Some organizations have created crowdsourced apps for syndromic surveillance, where people can report their symptoms to help researchers map areas with concentration of COVID-19 symptoms. [3]
Initial use of ECMO in COVID-19 patients from China early in the pandemic suggested poor outcomes, with less than 90% mortality. [83] In March 2020, the ELSO registry began collecting data on the worldwide use of ECMO for patients with COVID-19 and reporting this data on the ELSO website in real time.
Fractional dose vaccination is a strategy that trades societal benefit for individual vaccine efficacy, [25] has proven to be effective in randomized trials in poverty diseases, [26] [27] and in epidemiologic models [28] was thought to hold a significant potential for shortening the COVID-19 pandemic when vaccine supply is limited. [25]
The COVID-19 vaccination campaign in the United States is an ongoing mass immunization campaign for the COVID-19 pandemic in the United States.The Food and Drug Administration (FDA) first granted emergency use authorization to the Pfizer–BioNTech vaccine on December 10, 2020, [7] and mass vaccinations began four days later.
The report says that "the global pandemic alert system is not fit for purpose" and that the "World Health Organization has been underpowered to do the job." [224] Norwegian lawmakers nominated the WHO and COVAX for the 2021 Nobel Peace Prize, for their work to provide COVID-19 vaccines to low-income countries. [225]
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