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Renal corpuscles are composed of 4 cell types: fenestrated endothelium, mesangial cells, podocytes and parietal epithelial cells of Bowman's capsule. [101] At least 16 different cell types make up the renal tubules. [102] The tubules themselves are divided into at least 14 segments, [102] which differ in cell types and functions. [103]
The collecting duct system of the kidney consists of a series of tubules and ducts that physically connect nephrons to a minor calyx or directly to the renal pelvis.The collecting duct participates in electrolyte and fluid balance through reabsorption and excretion, processes regulated by the hormones aldosterone and vasopressin (antidiuretic hormone).
This filtrate then flows along the length of the nephron, which is a tubular structure lined by a single layer of specialized cells and surrounded by capillaries. The major functions of these lining cells are the reabsorption of water and small molecules from the filtrate into the blood, and the secretion of wastes from the blood into the urine.
White blood cell casts represent infection or inflammation involving the kidneys; [120] they can occur in pyelonephritis, but are absent in lower urinary tract infections. [121] Following injury to the renal tubules, renal tubular epithelial cell casts may be seen in the urine. [122]
The main functions of the urinary system and its components are to: Regulate blood volume and composition (e.g. sodium, potassium and calcium) Regulate blood pressure. Regulate pH homeostasis of the blood. Contributes to the production of red blood cells by the kidney. Helps synthesize calcitriol (the active form of Vitamin D).
Uriniferous tubules: any of the small tubules that are the excretory units of the vertebrate kidney; Uveoscleral pathway: a tubule that drains excess aqueous humor; Vasa efferentia: convoluted tubules that lead from the rete testis to the vas deferens and form the head of the epididymis [2]
Blood tests are also used to assess kidney function. These include tests that are intended to directly measure the function of the kidneys, as well as tests that assess the function of the kidneys by looking for evidence of problems associated with abnormal function. One of the measures of kidney function is the glomerular filtration rate (GFR).
Kidney function is tested by using blood tests and urine tests. The most common blood tests are creatinine, urea and electrolytes. Urine tests such as urinalysis can evaluate for pH, protein, glucose, and the presence of blood.