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2. Lenalidomide - Wikipedia

   en.wikipedia.org/wiki/Lenalidomide

   Lenalidomide, sold under the brand name Revlimid among others, is a medication used to treat multiple myeloma, smoldering myeloma, and myelodysplastic syndromes (MDS). [8] For multiple myeloma, it is a first line treatment, and is given with dexamethasone. [8] It is taken by mouth. [8]

3. Celgene Provides REVLIMID® Regulatory Update - AOL

   www.aol.com/news/2013-02-11-celgene-provides...

   Celgene Provides REVLIMID ® Regulatory Update REVLIMID Granted Approval for Treatment of Patients with Relapsed or Refractory Multiple Myeloma in China REVLIMID ...

4. Cereblon E3 ligase modulator - Wikipedia

   en.wikipedia.org/wiki/Cereblon_E3_ligase_modulator

   This disrupts the positive feedback loop between the two growth factors, possibly causing both multiple birth defects and anti-myeloma effects. Findings also support the hypothesis that an increase in the expression of cereblon is an essential element of the anti-myeloma effect of both lenalidomide and pomalidomide. [ 29 ]

5. Multiple myeloma - Wikipedia

   en.wikipedia.org/wiki/Multiple_myeloma

   Multiple myeloma is the second-most prevalent blood cancer (10%) after non-Hodgkin's lymphoma. [154] It represents about 1.8% of all new cancers and 2.1% of all cancer deaths. [7] Multiple myeloma affects slightly more men than women.

6. Celgene's Multiple Myeloma Powerhouse - AOL

   www.aol.com/news/2013-08-22-celgenes-multiple...

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7. Still Revving Up With Revlimid - AOL

   www.aol.com/.../02/08/still-revving-up-with-revlimid

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8. Myelodysplastic syndrome - Wikipedia

   en.wikipedia.org/wiki/Myelodysplastic_syndrome

   [24] [25] By 2005, lenalidomide, a chemotherapy drug, was recognized to be effective in MDS patients with the 5q- syndrome, [26] and in December 2005, the US FDA approved the drug for this indication. Patients with isolated 5q-, low IPSS risk, and transfusion dependence respond best to lenalidomide. Typically, prognosis for these patients is ...

9. Has Myeloma Met Its Match in Amgen's Kyprolis?

   www.aol.com/2013/11/18/has-myeloma-met-its-match...

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