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  2. Trazodone - Wikipedia

    en.wikipedia.org/wiki/Trazodone

    Trazodone, sold under many brand names, [1] is an antidepressant medication [20] used to treat major depressive disorder, anxiety disorders, and insomnia. [20] It is a phenylpiperazine compound of the serotonin antagonist and reuptake inhibitor (SARI) class.

  3. Tasimelteon - Wikipedia

    en.wikipedia.org/wiki/Tasimelteon

    A phase III insomnia trial was conducted in 2006. [12] A second phase III trial on insomnia, this time concerning primary insomnia, was completed in June 2008. [13] In 2010, the FDA granted orphan drug status to tasimelteon, then regarded as an investigational medication, for use in totally blind adults with N24HSWD. [14] (Through mechanisms ...

  4. List of psychotropic medications - Wikipedia

    en.wikipedia.org/wiki/List_of_psychotropic...

    Serentil (mesoridazine) – an antipsychotic drug used in the treatment of schizophrenia [1] Seroquel and Seroquel XR – atypical antipsychotic used to treat schizophrenia and bipolar disorder. Used off-label to treat insomnia; Sonata – a non-benzodiazepine hypnotic

  5. List of investigational sleep drugs - Wikipedia

    en.wikipedia.org/wiki/List_of_investigational...

    This is a list of investigational sleep drugs, or drugs for the treatment of sleep disorders that are currently under development for clinical use but are not yet approved. Chemical/generic names are listed first, with developmental code names, synonyms, and brand names in parentheses.

  6. Daridorexant - Wikipedia

    en.wikipedia.org/wiki/Daridorexant

    Daridorexant is indicated for the treatment of adults with insomnia characterized by difficulties with sleep onset and/or sleep maintenance. [1] The medication has been found to significantly improve latency to persistent sleep (LPS), wake after sleep onset (WASO), and subjective total sleep time (TST) in regulatory clinical trials. [1]

  7. Melatonin receptor agonist - Wikipedia

    en.wikipedia.org/wiki/Melatonin_receptor_agonist

    The Food and Drug Administration (FDA) granted tasimelteon orphan drug designation status for blind individuals without light perception with non-24-hour sleep–wake disorder in January the same year, [citation needed] and final FDA approval for the same purpose was achieved in January 2014 under the trade name Hetlioz. [10]

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