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This is a list of adverse effects of the antidepressant trazodone, sorted by frequency of occurrence. [1] [2] [3] Very common.
Trazodone lacks any affinity for the muscarinic acetylcholine receptors, so does not produce anticholinergic side effects. mCPP, a non-selective serotonin receptor modulator and serotonin releasing agent , is an active metabolite of trazodone and has been suggested to possibly play a role in its therapeutic benefits.
However, deprescribing may be considered if a patient experiences side effects like rapid heart rate, anxiety, or bone loss, or if their thyroid function tests normalize.” ...
In toxicology, the median lethal dose, LD 50 (abbreviation for "lethal dose, 50%"), LC 50 (lethal concentration, 50%) or LCt 50 is a toxic unit that measures the lethal dose of a given substance. [1] The value of LD 50 for a substance is the dose required to kill half the members of a tested population after a specified test duration.
The protective index is similar to the therapeutic index, but concerns toxicity (TD 50) rather than lethality (LD 50); thus, the protective index is a smaller ratio. Toxicity can take many forms, as drugs typically have multiple side effects of varying severity, so a specific criterion of toxicity must be specified for the protective index to ...
Luigi Mangione, who authorities accuse of murdering UnitedHealthcare CEO Brian Thompson, allegedly wrote in a notebook that he considered bombing Manhattan to carry out the killing but did not ...
A man in Michigan has been accused of killing his own mother before allegedly shooting his neighbor. Roger Schweda, 40, was arraigned on Monday, Dec. 9 of two counts of open murder and two counts ...
Chemical structure of the serotonin antagonist and reuptake inhibitor trazodone.. Serotonin antagonist and reuptake inhibitors (SARIs) are a class of drugs used mainly as antidepressants, but also as anxiolytics and hypnotics.