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  2. Adrenal insufficiency - Wikipedia

    en.wikipedia.org/wiki/Adrenal_insufficiency

    In adrenal insufficiency, there is a deficiency in cortisol production which may be accompanied by a deficiency in aldosterone production (predominantly in primary adrenal insufficiency). [2] [3] Depending on the cause and type of adrenal insufficiency, the mechanism of the disease differs. Generally, the symptoms manifest through the systemic ...

  3. Addison's disease - Wikipedia

    en.wikipedia.org/wiki/Addison's_disease

    Cortisol Aldosterone. In suspected cases of Addison's disease, demonstration of low adrenal hormone levels even after appropriate stimulation (called the ACTH stimulation test or synacthen test) with synthetic pituitary ACTH hormone tetracosactide is needed for the diagnosis. Two tests are performed, the short and the long test.

  4. Hypoaldosteronism - Wikipedia

    en.wikipedia.org/wiki/Hypoaldosteronism

    Hypoaldosteronism is an endocrinological disorder characterized by decreased levels of the hormone aldosterone. Similarly, isolated hypoaldosteronism is the condition of having lowered aldosterone without corresponding changes in cortisol. [1] (The two hormones are both produced by the adrenals.)

  5. Aldosterone - Wikipedia

    en.wikipedia.org/wiki/Aldosterone

    Aldosterone is the main mineralocorticoid steroid hormone produced by the zona glomerulosa of the adrenal cortex in the adrenal gland. [4] [5] It is essential for sodium conservation in the kidney, salivary glands, sweat glands, and colon. [6]

  6. Cortisol - Wikipedia

    en.wikipedia.org/wiki/Cortisol

    Cortisol is a steroid hormone in the glucocorticoid class of hormones and a stress hormone.When used as medication, it is known as hydrocortisone.. It is produced in many animals, mainly by the zona fasciculata of the adrenal cortex in an adrenal gland. [1]

  7. ACTH stimulation test - Wikipedia

    en.wikipedia.org/wiki/ACTH_stimulation_test

    Usually doubling to quadrupling from a low base aldosterone value is what is seen in secondary adrenal insufficiency. Decoupling of aldosterone in the ACTH stimulation test is possible (i.e. 2 ng/dl stimming to 20). [21] A result of doubling or more of aldosterone may help in tandem with a cortisol stimulation that doubled or more confirm a ...

  8. Adrenal crisis - Wikipedia

    en.wikipedia.org/wiki/Adrenal_crisis

    Adrenal insufficiency can be diagnosed by testing renin, dehydroepiandrosterone sulfate, aldosterone, serum cortisol, and ACTH levels. [14] A high cortisol level of more than 13 to 15 mg/dL can rule out the diagnosis.

  9. Congenital adrenal hyperplasia due to 17α-hydroxylase deficiency

    en.wikipedia.org/wiki/Congenital_adrenal...

    Because of the normal aldosterone level, hypertension is not expected. Normal cortisol level can be explained by the strong negative feedback mechanism of cortisol on hypothalamus-pituitary axis system. That is, in the beginning, 17,20-lyase deficiency will block synthesis of sex steroid hormones, forcing the pathways to produce more cortisol.

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