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The inner ear sensory epithelium is highly conserved among vertebrates, which gives hope that animal models, especially mammal models such as mice, are very applicable to clinical use in humans. [33] The development of human therapies require research in human mammalian cells, perhaps inner ear epithelial organoids.
Sound is transmitted to the inner ear via vibration of the tympanic membrane, leading to movement of the middle ear bones (malleus, incus, and stapes). Movement of the stapes on the oval window generates a pressure wave in the perilymph within the cochlea, causing the basilar membrane to vibrate. Sounds of different frequencies vibrate ...
In medicine, an ossicular replacement prosthesis is a device intended to be implanted for the functional reconstruction of segments of the ossicles and facilitates the conduction of sound waves from the tympanic membrane to the inner ear. [1]
The inner ear (internal ear, auris interna) is the innermost part of the vertebrate ear. In vertebrates , the inner ear is mainly responsible for sound detection and balance. [ 1 ] In mammals , it consists of the bony labyrinth , a hollow cavity in the temporal bone of the skull with a system of passages comprising two main functional parts: [ 2 ]
The superior semicircular canal dehiscence syndrome (SSCDS) is a set of hearing and balance symptoms that a rare disease/disorder of the inner ear's superior semicircular canal/duct induces. [ 3 ] [ 4 ] [ 5 ] The symptoms are caused by a thinning or complete absence of the part of the temporal bone overlying the superior semicircular canal of ...
Neurotologic surgery generally refers to surgery of the inner ear, or surgery that involves entering the inner ear with risk to the hearing and balance organs, including labyrinthectomy, cochlear implant surgery, and surgery for tumors of the temporal bone, such as intracanalicular acoustic neuromas.
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Since the inner ear is not directly accessible to instruments, identification is by patient report of the symptoms and audiometric testing. Of those who present to their doctor with sensorineural hearing loss, 90% report having diminished hearing, 57% report having a plugged feeling in ear, and 49% report having ringing in ear ().