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Chronic consumption of alcohol results in the secretion of pro-inflammatory cytokines (TNF-alpha, interleukin 6 and interleukin 8), oxidative stress, lipid peroxidation, and acetaldehyde toxicity. These factors cause inflammation, apoptosis and eventually fibrosis of liver cells. Why this occurs in only a few individuals is still unclear.
The American Heart Association states that drinking too much alcohol increases health risks including cardiovascular disease precursors such as obesity, high blood pressure, high triglycerides and also heart attacks and strokes. They warn that "We’ve all seen the headlines about studies associating light or moderate drinking with health ...
May Cause Alcohol Dependence “Regular or excessive alcohol consumption can lead to alcohol-related problems, including addiction, liver damage, and increased risk of certain cancers,” says ...
Alcohol can also increase specific hormones, such as estrogen, which may raise the risk of hormone-related cancers, particularly breast cancer. Another way alcohol can contribute to cancer growth ...
Higher triglycerides: Alcohol consumption can raise triglyceride levels, a type of fat in the blood. High triglyceride levels are a risk factor for heart disease. High triglyceride levels are a ...
Alcohol affects the nutritional state of chronic drinkers. It can decrease food consumption and lead to malabsorption. It can also create imbalances in skeletal muscle mass and cause muscle wasting. Chronic consumption of alcohol can also increase the breakdown of important proteins in the body which can affect gene expression. [157]
This can cause damage, inflammation, and other complications. ... Having high cholesterol or triglycerides. ... Speaking to a healthcare provider about medication that can help curb alcohol cravings.
Females are more susceptible to alcohol-associated liver injury and are therefore at higher risk of alcohol-associated hepatitis. [7] Certain genetic variations in the PNPLA3-encoding gene, which codes for an enzyme involved in triglyceride metabolism in adipose tissue are thought to influence disease severity. [7]