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  2. Trimethoprim/sulfamethoxazole - Wikipedia

    en.wikipedia.org/wiki/Trimethoprim/sulfamethoxazole

    The effects of trimethoprim causes a backlog of dihydrofolate (DHF) and this backlog can work against the inhibitory effect the drug has on tetrahydrofolate biosynthesis. This is where the sulfamethoxazole comes in; its role is in depleting the excess DHF by preventing it from being synthesised in the first place.

  3. Trimethoprim - Wikipedia

    en.wikipedia.org/wiki/Trimethoprim

    Trimethoprim (TMP) is an antibiotic used mainly in the treatment of bladder infections. [1] Other uses include for middle ear infections and travelers' diarrhea. [1] With sulfamethoxazole or dapsone it may be used for Pneumocystis pneumonia in people with HIV/AIDS.

  4. List of antibiotics - Wikipedia

    en.wikipedia.org/wiki/List_of_antibiotics

    Bactrim, Septra Sulfonamidochrysoidine (archaic) Prontosil: Tetracyclines(Bs) Demeclocycline: Declomycin: Syphilis, chlamydial infections, Lyme disease, mycoplasmal infections, acne rickettsial infections, malaria [note 1] Gastrointestinal upset; Sensitivity to sunlight; Potential toxicity to mother and fetus during pregnancy

  5. Urinary anti-infective agent - Wikipedia

    en.wikipedia.org/wiki/Urinary_anti-infective_agent

    Urinary tract infection in pediatric patients is a significant clinical issue, affecting approximately 7% of fevered infants and children. [43] If left untreated, the infection can ascend from the bladder to the kidneys, resulting in acute pyelonephritis, which leads to hypertension , kidney scarring , and end-stage kidney disease .

  6. Isoniazid/pyridoxine/sulfamethoxazole/trimethoprim - Wikipedia

    en.wikipedia.org/wiki/Isoniazid/pyridoxine/sulfa...

    This page was last edited on 25 February 2025, at 14:20 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.

  7. List of β-lactam antibiotics - Wikipedia

    en.wikipedia.org/wiki/List_of_β-lactam_antibiotics

    The β-lactam core structures. (A) A penam.(B) A carbapenam.(C) An oxapenam.(D) A penem.(E) A carbapenem.(F) A monobactam.(G) A cephem.(H) A carbacephem.(I) An oxacephem. This is a list of common β-lactam antibiotics—both administered drugs and those not in clinical use—organized by structural class.

  8. Broad-spectrum antibiotic - Wikipedia

    en.wikipedia.org/wiki/Broad-spectrum_antibiotic

    A colored electron microscopy image of methicillin-resistant staphylococcus aureus (), a bacterium commonly targeted by broad-spectrum antibioticsA broad-spectrum antibiotic is an antibiotic that acts on the two major bacterial groups, Gram-positive and Gram-negative, [1] or any antibiotic that acts against a wide range of disease-causing bacteria. [2]

  9. Sulfamethoxazole - Wikipedia

    en.wikipedia.org/wiki/Sulfamethoxazole

    Its Tmax (or time to reach maximum drug concentration in plasma) occurs 1 to 4 hours after oral administration. The mean serum half-life of sulfamethoxazole is 10 hours. [8] However, the half-life of the drug noticeably increases in people with creatinine clearance rates equal to or less than 30 mL/minute.

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