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Well, there’s no magic time, but you should take metformin at the same time each day and with food to avoid gastrointestinal side effects. If you’re taking extended-release metformin tablets ...
If you combine daily metformin use with regular exercise and a low-carb diet, you may also have noticeable weight loss though it may take two to three months to see this, Dr. Gupta adds. Signs ...
People with type 2 diabetes taking metformin face lower risks of death from heart disease. The drug helps to treat gestational diabetes and polycystic ovarian syndrome, both of which cause high ...
In patients with diabetes mellitus type 1, alpha-glucosidase inhibitors use has not been officially approved by the Food and Drug Administration in the US but some data exists on the effectiveness in this population, showing potential benefits weighted against an increased risk of hypoglycemia.
Pioglitazone/metformin is indicated as an adjunct to diet and exercise: [medical citation needed] To improve glycemic control in patients with type 2 diabetes, or; For patients who are already treated with a separate combination of pioglitazone and metformin, For patients whose diabetes is not adequately controlled with metformin alone, or
Vildagliptin/metformin is indicated in the treatment of type-2 diabetes mellitus: [4] [6] [7] it is indicated in the treatment of adults who are unable to achieve sufficient glycaemic control at their maximally tolerated dose of oral metformin alone or who are already treated with the combination of vildagliptin and metformin as separate tablets.
Before taking metformin, let your doctor know if you have any medical conditions like kidney or liver problems or type 1 diabetes, or if you’re pregnant or breastfeeding.
In other words, in a person that is intolerant to a medication, it is possible for a dose of 10 mg to "feel" like a dose of 100 mg, resulting in an overdose—a "normal" dose can be a "toxic" dose in these individuals, leading to clinically significant effects. There is also an aspect of drug intolerance that is subjective.