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Phenobarbital, also known as phenobarbitone or phenobarb, sold under the brand name Luminal among others, is a medication of the barbiturate type. [6] It is recommended by the World Health Organization (WHO) for the treatment of certain types of epilepsy in developing countries . [ 8 ]
Tedral is also composed of phenobarbital, therefore, it is contraindicated for individuals with: [8] [5] [20] Hypersensitivity to phenobarbital, barbiturates or any component of the formulation. A history/manifest or latent porphyria; Liver impairment; Nephritic syndrome (at high dose) A history of sedative-hypnotic drug addiction
Corvalol. Corvalol (Корвалол, Corvalolum, Korvalol) is a tranquilizer based on the herb valerian (Valeriana officinalis) root, as well peppermint oil Mentha piperita and hop extract Humulus lupulus and the barbiturate phenobarbital, popular in Eastern Europe and the former Soviet Union as a heart medication.
Methylphenobarbital (), also known as mephobarbital (USAN, JAN) and mephobarbitone (), marketed under brand names such as Mebaral, Mephyltaletten, Phemiton, and Prominal, is a drug which is a barbiturate derivative and is used primarily as an anticonvulsant, [2] but also as a sedative and anxiolytic.
Only the phenobarbital group demonstrated a significant change in pain type compared to belladonna alkaloids at the end of the study with an approximate 48% response rate. Patients on Donnatal® tablets, belladonna alkaloids, and placebo all had non-significant (p > 0.149) shifts to dull pain, 39.5%, 52.3%, and 40.4%, respectively compared to ...
It has similar liver enzyme inducing effects to the closely related drug phenobarbital, which may be exploited in some clinical applications. [2] [3] References
Barbital, then called "Veronal", was first synthesized in 1902 by German chemists Emil Fischer and Joseph von Mering, who published their discovery in 1903. [2] Barbital was prepared by condensing diethylmalonic ester with urea in the presence of sodium ethoxide, or by adding at least two molar equivalents of ethyl iodide to the silver salt of malonylurea (barbituric acid) or possibly to a ...
Aprobarbital (or aprobarbitone), sold under the brand names Oramon, Somnifaine, and Allonal, is a barbiturate derivative invented in the 1920s by Ernst Preiswerk. It has sedative, hypnotic, and anticonvulsant properties, and was used primarily for the treatment of insomnia. [2]