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For example, Δ 9-THC has an EC 50 of 250 nM at CB 1 and 1157 nM at CB 2, whereas PB-22 has an EC 50 of 5.1 nM at CB 1 and 37 nM at CB 2. [8] Adverse effects observed due to synthetic cannabinoid use include acute kidney injury , cardiac toxicity , seizure , stroke , tremor , hypokalemia , and rhabdomyolysis .
Following the war, fear over soldiers returning home still harboring addiction permeated the United States. However, this anxiety proved to be misplaced, as the Special Action Office for Drug Abuse Prevention (SAODAP) found that addiction and usage rates “essentially decreased to pre-war levels” after the soldiers’ return.” [10] Studies done during operation golden flow suggested that ...
There is a slight increase in dose proportionality in terms of peak and area-under-the-curve levels of THC with increasing oral doses over a range of 2.5 to 10 mg. [22] A high-fat meal delays time to peak concentrations of oral THC by 4 hours on average and increases area-under-the-curve exposure by 2.9-fold, but peak concentrations are not ...
Detoxification (often shortened to detox and sometimes called body cleansing) is a type of alternative-medicine treatment which aims to rid the body of unspecified "toxins" – substances that proponents claim accumulate in the body over time and have undesirable short-term or long-term effects on individual health.
Cannabis concentrate, also called marijuana concentrate, marijuana extract, or cannabis extract, is a tetrahydrocannabinol (THC) and/or cannabidiol (CBD) concentrated mass. Cannabis concentrates contain high THC levels that range from 40% to over 90%, [ 1 ] [ 2 ] stronger in THC content than high-grade marijuana, which normally measures around ...
[2] [3] In medicine, detoxification can be achieved by decontamination of poison ingestion and the use of antidotes as well as techniques such as dialysis and (in a limited number of cases) chelation therapy. [4] Many alternative medicine practitioners promote various types of detoxification such as detoxification diets.
Δ-8-tetrahydrocannabinol (delta-8-THC, [a] Δ 8-THC) is a psychoactive cannabinoid found in the cannabis plant. [1] It is an isomer of delta-9-tetrahydrocannabinol (delta-9-THC, Δ 9-THC), the compound commonly known as THC, with which it co-occurs in hemp; natural quantities of ∆ 8-THC found in hemp are low.
Tincture of cannabis, sometimes known as green dragon, is an alcoholic cannabis concentrate.The solubility of THC in ethanol is greater than 1 g/mL. [1]According to the European Medicines Agency (EMA) cannabis tinctures (tincturea) are a type of liquid cannabis extract obtained using ethanol, water, glycerol, propylene glycol and fatty oils as extraction solvents, depending on the type of ...
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