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  2. Xanomeline/trospium chloride - Wikipedia

    en.wikipedia.org/wiki/Xanomeline/trospium_chloride

    In March 2023, Karuna Therapeutics announced that KarXT had met its primary endpoint in a phase III trial, EMERGENT-3, and that it was submitting the drug for approval by the US Food and Drug Administration (FDA). [13] In November 2023, the FDA began its review and set the PDUFA date for September 2024. [14]

  3. Xanomeline - Wikipedia

    en.wikipedia.org/wiki/Xanomeline

    In March 2023, Karuna Therapeutics announced that KarXT had met its primary endpoint in a phase III trial, EMERGENT-3, and that it was submitting the drug for approval by the US Food and Drug Administration (FDA). [21] In September 2024, the combination drug was approved by the FDA. [6]

  4. 19 drug approvals in 2024 that had 'big clinical impact ... - AOL

    www.aol.com/19-drug-approvals-2024-had-093022917...

    GoodRx released a list of 19 of the most influential drugs and vaccines approved by the FDA in 2024 to treat a variety of conditions. These medications are “slated to make a big clinical impact."

  5. List of investigational antipsychotics - Wikipedia

    en.wikipedia.org/wiki/List_of_investigational...

    This is a list of investigational antipsychotics, or antipsychotics that are currently under development for clinical use but are not yet approved. Chemical/generic names are listed first, with developmental code names, synonyms, and brand names in parentheses. This list was last comprehensively updated in December 2017.

  6. List of therapeutic monoclonal antibodies - Wikipedia

    en.wikipedia.org/wiki/List_of_therapeutic...

    This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been withdrawn from market; consequently, the column Use does not necessarily indicate clinical usage. See the list of FDA-approved therapeutic monoclonal antibodies in the monoclonal antibody therapy page.

  7. List of drugs granted breakthrough therapy designation

    en.wikipedia.org/wiki/List_of_drugs_granted...

    In combination with palbociclib and fulvestrant for the treatment of adults with endocrine-resistant, PIK3CA-mutated, hormone receptor (HR)-positive, human epidermal growth-factor receptor 2 (HER2)-negative, locally advanced or metastatic breast cancer, as detected by an FDA-approved test, following recurrence on or after completing adjuvant ...

  8. PDUFA date - Wikipedia

    en.wikipedia.org/wiki/PDUFA_date

    The PDUFA date serves as a good first approximation of when a final decision on drug approval can be expected. Sponsors frequently publish PDUFA dates for their pending applications, [1] and while there is no official list of PDUFA dates, [10] several websites collect PDUFA dates from press announcements in a calendar form.

  9. US FDA approves Amgen drug for small cell lung cancer - AOL

    www.aol.com/news/us-fda-approves-amgen-drug...

    US FDA approves Amgen drug for small cell lung cancer. May 17, 2024 at 10:56 AM (This May 16 story has been officially corrected to change the pricing estimate in paragraph 4)