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These side effects may occur in as many as 90% of men treated with bicalutamide monotherapy, [29] but gynecomastia is generally reported to occur in 70 to 80% of patients. [30] In the EPC trial, at a median follow-up of 7.4 years, breast pain and gynecomastia respectively occurred in 73.6% and 68.8% of men treated with 150 mg/day bicalutamide ...
The core side effects of NSAAs such as gynecomastia, sexual dysfunction, and hot flashes occur at similar rates with the different drugs. [ 48 ] [ 49 ] Conversely, bicalutamide is associated with a significantly lower rate of diarrhea compared to flutamide.
The side effects of nicergoline are usually limited to nausea, hot flushes, mild gastric upset, hypotension and dizziness. [6] At high drug dosages, bradycardia, increased appetite, agitation, diarrhea and perspiration were reported. Most of the available literature suggests that the side effects of nicergoline are mild and transient. [2]
[17] [4] It also has functional antiandrogenic effects by decreasing the circulating free fractions of androgens. [18] CPA is a progestin (synthetic progestogen ), or an agonist of the progesterone receptors , the biological target of progestogens like progesterone .
Type A: augmented pharmacological effects, which are dose-dependent and predictable [5]; Type A reactions, which constitute approximately 80% of adverse drug reactions, are usually a consequence of the drug's primary pharmacological effect (e.g., bleeding when using the anticoagulant warfarin) or a low therapeutic index of the drug (e.g., nausea from digoxin), and they are therefore predictable.
Side effects [ edit ] Since little of the medication crosses the blood-brain barrier , this drug has less effect on the brain and therefore causes a reduced occurrence of the centrally-mediated effects (such as delusions , somnolence and inhibition of motor functions) which reduce the usefulness of some other anticholinergic drugs.
RSV vaccine side effects in older adults . The CDC lists the following as possible side effects of the RSV vaccine: Pain, redness, and swelling where the shot is given. Fatigue. Fever. Headache ...
Trihexyphenidyl (THP, benzhexol, trihex, marketed as Artane and others) is an antispasmodic drug used to treat stiffness, tremors, spasms, and poor muscle control. It is an agent of the antimuscarinic class and is often used in management of Parkinson's disease.