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  2. Neonatal isoerythrolysis - Wikipedia

    en.wikipedia.org/wiki/Neonatal_isoerythrolysis

    Immune mediated thrombocytopenia often occurs concurrently in mule foals suffering from neonatal isoerythrolysis. [2] Some mares have natural alloantibodies, usually to the Ca blood group, without ever having a known exposure to that blood group. This is seen in 10% of Thoroughbred mares and 20% of Standardbred mares. [2]

  3. Warm antibody autoimmune hemolytic anemia - Wikipedia

    en.wikipedia.org/wiki/Warm_antibody_autoimmune...

    The most common antibody isotype involved in warm antibody AIHA is IgG, though sometimes IgA is found. The IgG antibodies attach to a red blood cell, leaving their F C portion exposed with maximal reactivity at 37 °C (versus cold antibody induced hemolytic anemia whose antibodies only bind red blood cells at low body temperatures, typically 28–31 °C).

  4. Autoimmune hemolytic anemia - Wikipedia

    en.wikipedia.org/wiki/Autoimmune_hemolytic_anemia

    A hemolytic state exists whenever the red cell survival time is shortened from the normal average of 120 days. Hemolytic anemia is the hemolytic state in which anemia is present, and bone marrow function is inferentially unable to compensate for the shortened lifespan of the red cell. Immune hemolytic states are those, both anemic and nonanemic ...

  5. Coombs test - Wikipedia

    en.wikipedia.org/wiki/Coombs_test

    The direct Coombs test is used to test for autoimmune hemolytic anemia, a condition where the immune system breaks down red blood cells, leading to anemia. The direct Coombs test is used to detect antibodies or complement proteins attached to the surface of red blood cells. To perform the test, a blood sample is taken and the red blood cells ...

  6. Acquired hemolytic anemia - Wikipedia

    en.wikipedia.org/wiki/Acquired_hemolytic_anemia

    Cold antibody autoimmune hemolytic anemia [2] Paroxysmal cold hemoglobinuria [2] Drug-induced autoimmune hemolytic anemia [2] Alloimmune hemolytic anemia [1] Hemolytic disease of the newborn (HDN) [1] Rh disease (Rh D) [1] ABO hemolytic disease of the newborn [1] Anti-Kell hemolytic disease of the newborn [1] Rhesus c hemolytic disease of the ...

  7. Spherocytosis - Wikipedia

    en.wikipedia.org/wiki/Spherocytosis

    Spherocytes are found in immunologically-mediated hemolytic anemias and in hereditary spherocytosis, but the former would have a positive direct Coombs test and the latter would not. The misshapen but otherwise healthy red blood cells are mistaken by the spleen for old or damaged red blood cells and it thus constantly breaks them down, causing ...

  8. Drug-induced autoimmune hemolytic anemia - Wikipedia

    en.wikipedia.org/wiki/Drug-induced_autoimmune...

    A positive direct antiglobulin test differentiates immune-mediated hemolytic anemia from a nonimmune-mediated cause. Other situations such as liver disease, post-transfusion or immunoglobulin administration, renal disease, and malignancy can cause a positive direct antiglobulin test. [1]

  9. Immune-mediated thrombocytopaenia - Wikipedia

    en.wikipedia.org/wiki/Immune-mediated...

    Therapeutic plasma exchange (TPE) is a novel treatment for immune-mediated diseases and little research has been done for the effectiveness of TPE and patients with IMT. [15] TPE requires removing the patient's plasma which contains antibodies and replacing it with fluids such as sodium chloride , frozen plasma, packed red blood cells, and ...

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