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2. High-throughput screening - Wikipedia

   en.wikipedia.org/wiki/High-throughput_screening

   High-throughput screening (HTS) is a method for scientific discovery especially used in drug discovery and relevant to the fields of biology, materials science [1] and chemistry. [ 2 ] [ 3 ] Using robotics , data processing/control software, liquid handling devices, and sensitive detectors, high-throughput screening allows a researcher to ...

3. Drug discovery - Wikipedia

   en.wikipedia.org/wiki/Drug_discovery

   In the fields of medicine, biotechnology, and pharmacology, drug discovery is the process by which new candidate medications are discovered. [1]Historically, drugs were discovered by identifying the active ingredient from traditional remedies or by serendipitous discovery, as with penicillin.

4. Hit to lead - Wikipedia

   en.wikipedia.org/wiki/Hit_to_lead

   Hit to lead (H2L) also known as lead generation is a stage in early drug discovery where small molecule hits from a high throughput screen (HTS) are evaluated and undergo limited optimization to identify promising lead compounds.

5. Assay - Wikipedia

   en.wikipedia.org/wiki/Assay

   A high throughput assay can be either an endpoint or a kinetic assay usually done on an automated platform in 96-, 384- or 1536-well microplate formats (High Throughput Screening). Such assays are able to test large number of compounds or analytes or make functional biological readouts in response to a stimuli and/or compounds being tested.

6. Drug development - Wikipedia

   en.wikipedia.org/wiki/Drug_development

   Drug development is the process of bringing a new pharmaceutical drug to the market once a lead compound has been identified through the process of drug discovery.It includes preclinical research on microorganisms and animals, filing for regulatory status, such as via the United States Food and Drug Administration for an investigational new drug to initiate clinical trials on humans, and may ...

7. Phenotypic screening - Wikipedia

   en.wikipedia.org/wiki/Phenotypic_screening

   Phenotypic screening is a type of screening ... The pharmaceutical company Eli Lilly has ... Bailey D (August 2014). "Phenotypic screening in cancer drug discovery ...