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Enterovirus 71 (EV71), also known as Enterovirus A71 (EV-A71), is a virus of the genus Enterovirus in the Picornaviridae family, [1] notable for its role in causing epidemics of severe neurological disease and hand, foot, and mouth disease in children. [2]
Poliomyelitis (/ ˌ p oʊ l i oʊ ˌ m aɪ ə ˈ l aɪ t ɪ s / POH-lee-oh-MY-ə-LY-tiss), commonly shortened to polio, is an infectious disease caused by the poliovirus. [1] Approximately 75% of cases are asymptomatic; [5] mild symptoms which can occur include sore throat and fever; in a proportion of cases more severe symptoms develop such as headache, neck stiffness, and paresthesia.
Around age two, Little was infected with poliomyelitis which caused a deformed foot. He decided to enter the medical profession, with the intention of finding a cure for his foot. [154] [155] Elsie MacGill: 1905–1980 The first female aircraft designer in the world, MacGill was afflicted with polio at the age of 24.
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The CDC recorded 32 cases of acute flaccid myelitis across 17 states in the first half of this year. The median age of affected patients is 7 years old.
Historically, poliomyelitis was the most significant disease caused by an enterovirus, namely poliovirus. There are 81 non-polio and 3 polio enteroviruses that can cause disease in humans. Of the 81 non-polio types, there are 22 Coxsackie A viruses, 6 Coxsackie B viruses, 28 echoviruses, and 25 other enteroviruses. [3]
Most people infected with polio don’t have any symptoms, but it can cause fever, headaches, vomiting and stiffness of the spine. In severe cases, polio can invade the nervous system and cause paralysis within hours, according to the WHO. The U.N. agency estimates that 1 in 200 polio cases results in permanent paralysis, usually of the legs.