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The Henderson–Hasselbalch equation can be used to model these equilibria. It is important to maintain this pH of 7.4 to ensure enzymes are able to work optimally. [10] Life threatening Acidosis (a low blood pH resulting in nausea, headaches, and even coma, and convulsions) is due to a lack of functioning of enzymes at a low pH. [10]
The pH range is commonly given as zero to 14, but a pH value can be less than 0 for very concentrated strong acids or greater than 14 for very concentrated strong bases. [2] The pH scale is traceable to a set of standard solutions whose pH is established by international agreement. [3]
Speciation of ions refers to the changing concentration of varying forms of an ion as the pH of the solution changes. [1]The ratio of acid, AH and conjugate base, A −, concentrations varies as the difference between the pH and the pK a varies, in accordance with the Henderson-Hasselbalch equation.
For calculating concentrations, an ICE table can be used. [16] [1] ICE stands for initial, change, and equilibrium. The pH of a weak acid solution being titrated with a strong base solution can be found at different points along the way. These points fall into one of four categories: [17] initial pH; pH before the equivalence point; pH at the ...
The equation can only be applied when the purged volume of vapor or gas is replaced with "clean" air or gas. For example, the equation can be used to calculate the time required at a certain ventilation rate to reduce a high carbon monoxide concentration in a room.
As seen above, the strength of a base depends primarily on pH. To help describe the strengths of weak bases, it is helpful to know the percentage protonated-the percentage of base molecules that have been protonated. A lower percentage will correspond with a lower pH because both numbers result from the amount of protonation.
In chemistry, acid value (AV, acid number, neutralization number or acidity) is a number used to quantify the acidity of a given chemical substance.It is the quantity of base (usually potassium hydroxide (KOH)), expressed as milligrams of KOH required to neutralize the acidic constituents in 1 gram of a sample.
Acid-neutralizing capacity or ANC in short is a measure for the overall buffering capacity against acidification of a solution, e.g. surface water or soil water.. ANC is defined as the difference between cations of strong bases and anions of strong acids (see below), or dynamically as the amount of acid needed to change the pH value from the sample's value to a chosen different value. [1]