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Data from studies conducted on women taking antiepileptic drugs for non-epileptic reasons, including depression and bipolar disorder, show that if high doses of the drugs are taken during the first trimester of pregnancy then there is the potential of an increased risk of congenital malformations.
However, long-term prophylactic treatment of epilepsy may have considerable drawbacks, most importantly decreased antiepileptic effects due to drug tolerance which may render long-term therapy less effective. [10] Other antiepileptic drugs may therefore be preferred for the long-term management of epilepsy.
In 2006, the FDA approved Sepracor's drug Brovana to treat chronic obstructive pulmonary disease (COPD). [3] In 2008, Bial agreed with the company to produce and market its antiepileptic drug Aptiom at Sepracor's facilities and supervised by Bial. [4] Aptiom subsequently received FDA approval in 2013 to treat partial onset seizures.
Depakote (valproic acid/sodium valproate) – an antiepileptic and mood stabilizer used to treat bipolar disorder, neuropathic pain and others; sometimes called an antimanic medication. Depakene is the trade name for the same drug prepared without sodium. Desyrel – an atypical antidepressant used to treat depression and insomnia
As with all other antiepileptic drugs approved by the FDA, gabapentin is labeled for an increased risk of suicide. Lower doses are recommended in those with kidney disease. [7] Gabapentin was first approved for use in the United Kingdom in 1993. [16] It has been available as a generic medication in the United States since 2004. [17]
In early 2023, the U.S. Food and Drug Administration (FDA) granted accelerated approval to a new Alzheimer’s drug called Leqembi. (Biogen, a biotechnology company, and Eisai, a pharmaceutical ...
The combination was refused approval by the US Food and Drug Administration (FDA) in 2023. [11] It was approved for medical use in Canada in May 2023, [ 4 ] in Australia in March 2024, [ 1 ] and in the United States in October 2024.
A new opioid-free pain medication was approved by the U.S. Food and Drug Administration (FDA) on Thursday, marking a non-addictive alternative for patients. Journavx (suzetrigine), made by Vertex ...
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