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  2. Enalapril - Wikipedia

    en.wikipedia.org/wiki/Enalapril

    Enalapril, sold under the brand name Vasotec among others, is an ACE inhibitor medication used to treat high blood pressure, diabetic kidney disease, and heart failure. [5] For heart failure, it is generally used with a diuretic , such as furosemide . [ 6 ]

  3. Discovery and development of ACE inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    Enalapril. Lisiniopril. The most common adverse effects of Captopril, skin rash and loss of taste, are the same as caused by mercapto-containing penicillamine. Therefore, a group of researchers aimed at finding potent, selective ACE inhibitors that would not contain a mercapto (SH) function and would have a weaker chelating function.

  4. Cerebral vasodilator - Wikipedia

    en.wikipedia.org/wiki/Cerebral_vasodilator

    A cerebral vasodilator is a drug which acts as a vasodilator in the brain. [1] [2] They are used to improve blood flow in people with cerebrovascular insufficiency and to treat neurological disorders secondary to this condition. [2] A number of different cerebral vasodilators exist.

  5. Endothelium-derived hyperpolarizing factor - Wikipedia

    en.wikipedia.org/wiki/Endothelium-derived...

    The endothelium maintains vascular homeostasis through the release of active vasodilators.Although nitric oxide (NO) is recognized as the primary factor at level of arteries, increased evidence for the role of another endothelium-derived vasodilator known as endothelium-derived hyperpolarizing factor (EDHF) has accumulated in the last years.

  6. Vasoconstriction - Wikipedia

    en.wikipedia.org/wiki/Vasoconstriction

    Ambient temperature is an example of exogenous vasoconstriction. Cutaneous vasoconstriction will occur because of the body's exposure to the severe cold. Examples of endogenous factors include the autonomic nervous system, circulating hormones, and intrinsic mechanisms inherent to the vasculature itself (also referred to as the myogenic response).

  7. Potassium channel opener - Wikipedia

    en.wikipedia.org/wiki/Potassium_channel_opener

    Some examples include: Diazoxide [1] vasodilator used for hypertension, smooth muscle relaxing activity; Minoxidil [2] vasodilator used for hypertension, also used to treat hair loss; Nicorandil [3] vasodilator used to treat angina; Pinacidil [4] Retigabine, [5] [6] an anticonvulsant; Flupirtine, analgesic with muscle relaxant and ...

  8. Arteriolar vasodilator - Wikipedia

    en.wikipedia.org/wiki/Arteriolar_vasodilator

    Arteriolar vasodilators are substances or medications that preferentially dilate arterioles.When used on people with certain heart conditions, it causes a phenomenon known as the cardiac steal syndrome.

  9. Alpha-1 blocker - Wikipedia

    en.wikipedia.org/wiki/Alpha-1_blocker

    Post-traumatic stress disorder (PTSD) is a disabling mental condition that can develop following a traumatic experience; for example, it is especially common in military veterans and sexual assault survivors. Prazosin is commonly used as an antihypertensive, but because alpha-1-adrenergic activity has been connected to fear and startle ...

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