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Prucalopride, sold under brand names Resolor and Motegrity among others, is a medication acting as a selective, high affinity 5-HT 4 receptor agonist [4] which targets the impaired motility associated with chronic constipation, thus normalizing bowel movements.
Lubiprostone, sold under the brand name Amitiza among others, is a medication used in the management of chronic idiopathic constipation, predominantly irritable bowel syndrome-associated constipation in women and opioid-induced constipation. The drug is owned by Mallinckrodt and is marketed by Takeda Pharmaceutical Company. The drug was ...
Prolonged use of stimulant laxatives can create drug dependence by damaging the colon's haustral folds, making users less able to move feces through their colon on their own. A study of patients with chronic constipation found that 28% of chronic stimulant laxative users lost haustral folds over the course of one year, while none of the control ...
Ozempic and Wegovy, the blockbuster but costly GLP-1 drugs often used for weight loss, ... Linzess, treats chronic constipation, irritable bowel syndrome with constipation. Calquence, treats ...
In chronic constipation of unknown cause, the main treatment involves the increased intake of water and fiber (either dietary or as supplements). [18] The routine use of laxatives or enemas is discouraged, as having bowel movements may come to be dependent upon their use.
2. Try a laxative. An osmotic (better known as a laxative) is a type of medication that draws water into your bowel to unblock you. Polyethylene glycol and bisacodyl are popular options.Again ...
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