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Samoyeds can be affected by basement membrane disease of the kidneys. It is inherited through the X chromosome and is therefore more severe in affected male dogs. Findings in male dogs include the presence of protein and glucose in the urine and the inability to concentrate urine, and progression to kidney failure by the age of 9 months and death by 16 months. [3]
The typical mammalian kidney consists of a renal capsule, a peripheral cortex, an internal medulla, one or more renal calyces, and a renal pelvis. [7] Although the calyces or renal pelvis may be absent in some species. [7] The medulla is made up of one or more renal pyramids, [8] forming papillae with their innermost parts. [9]
In heterozygous females, whereby only one of the two X chromosomes carry the mutation, the disease develops slowly. [4] [5] The disease is specific to the Samoyed, in that the Samoyed is the only breed of dog to show the more rapid progression to kidney failure and death, as well as affecting males to a much more severe degree than females.
The asymmetry within the abdominal cavity, caused by the position of the liver, typically results in the right kidney being slightly lower and smaller than the left, and being placed slightly more to the middle than the left kidney. [10] [11] [12] The left kidney is approximately at the vertebral level T12 to L3, [13] and the right is slightly ...
Horseshoe kidney : A condition in which the lower poles of both kidneys are fused. The fusion alters the normal position of the collecting system, which may cause the absence of the expected renal sinus appearance in axial images. Crossed Fused Renal Ectopia: One kidney crosses over to the opposite side and fuses with the other kidney.
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The incidence rate of CKD in dogs was 15.8 cases per 10,000 dog years at risk. The mortality rate of CKD was 9.7 deaths per 10,000 dog years at risk. (Rates developed from a population of 600,000 insured Swedish dogs; one dog year at risk is one dog at risk for one year).
Details of structures vary tremendously from breed to breed, more than in any other animal species, wild or domesticated, [1] as dogs are highly variable in height and weight. The smallest known adult dog was a Yorkshire Terrier that stood only 6.3 cm (2.5 in) at the shoulder, 9.5 cm (3.7 in) in length along the head and body, and weighed only ...