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An immortalised cell line is a population of cells from a multicellular organism that would normally not proliferate indefinitely but, due to mutation, have evaded normal cellular senescence and instead can keep undergoing division. The cells can therefore be grown for prolonged periods in vitro. The mutations required for immortality can occur ...
In March 2020, the Cellosaurus created a page containing cell line information relevant to SARS-CoV-2 in response to the COVID-19 pandemic. [ 9 ] The Cellosaurus encyclopedia is widely recognized as an authoritative source for cell line information, providing unique identifiers [ 10 ] [ 11 ] and as source of curated information.
In cellular biology, stable cells are cells that multiply only when needed. They spend most of the time in the quiescent G 0 phase of the cell cycle but can be stimulated to enter the cell cycle when needed. Examples include the liver, the proximal tubules of the kidney and endocrine glands.
SH-SY5Y is a human derived cell line used in scientific research. The original cell line, called SK-N-SH, from which it was subcloned was isolated from a bone marrow biopsy taken from a four-year-old female with neuroblastoma. SH-SY5Y cells are often used as in vitro models of neuronal function and
Von Neumann's System of Self-Replication Automata with the ability to evolve (Figure adapted from Luis Rocha's Lecture Notes at Binghamton University [6]).i) the self-replicating system is composed of several automata plus a separate description (an encoding formalized as a Turing 'tape') of all the automata: Universal Constructor (A), Universal Copier (B), operating system (C), extra ...
A stem cell line is a group of stem cells that is cultured in vitro and can be propagated indefinitely. Stem cell lines are derived from either animal or human tissues and come from one of three sources: embryonic stem cells, adult stem cells, or induced pluripotent stem cells. They are commonly used in research and regenerative medicine.
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Disease and virology studies can use permanent cells to maintain cell count and accurately quantify the effects of vaccines. [1] Some embryology studies also use permanent cells to avoid harvesting embryonic cells from pregnant animals; since the cells are permanent, they may be harvested at a later age when an animal is fully developed. [4]
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