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Indigestion is a common problem and frequent reason for primary care physicians to refer patients to GI specialists. [38] Worldwide, dyspepsia affects about a third of the population. [ 39 ] It can affect a person's quality of life even if the symptoms within themselves are usually not life-threatening.
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The gastrointestinal tract (GI tract, digestive tract, alimentary canal) is the tract or passageway of the digestive system that leads from the mouth to the anus. The GI tract contains all the major organs of the digestive system, in humans and other animals, including the esophagus , stomach , and intestines .
Gastrointestinal physiology is the branch of human physiology that addresses the physical function of the gastrointestinal (GI) tract.The function of the GI tract is to process ingested food by mechanical and chemical means, extract nutrients and excrete waste products.
Other common symptoms that stomach disease might cause include indigestion or dyspepsia, vomiting, and in chronic disease, digestive problems leading to forms of malnutrition. [5]: 850–853 In addition to routine tests, an endoscopy might be used to examine or take a biopsy from the stomach. [5]: 848
A fourth phase of acid secretion is known as the basal state which occurs in the times between meals (interdigestive phase). The level of acid secretion during these times is regulated by body weight, individual, number of parietal cells, and time of day. Acid secretion is lowest in the morning before awakening and highest at night. [2]
In gastroenterology, esophageal pH monitoring is the current gold standard for diagnosis of gastroesophageal reflux disease (GERD). It provides direct physiologic measurement of acid in the esophagus and is the most objective method to document reflux disease, assess the severity of the disease and monitor the response of the disease to medical or surgical treatment.