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Viewed through a microscope, cardiac muscle cells are roughly rectangular, measuring 100–150μm by 30–40μm. [9] Individual cardiac muscle cells are joined at their ends by intercalated discs to form long fibers. Each cell contains myofibrils, specialized protein contractile fibers of actin and myosin that slide past each other
Intercalated discs or lines of Eberth are microscopic identifying features of cardiac muscle. Cardiac muscle consists of individual heart muscle cells (cardiomyocytes) connected by intercalated discs to work as a single functional syncytium. By contrast, skeletal muscle consists of multinucleated muscle
The main function of striated muscle tissue is to create force and contract. These contractions in cardiac muscle will pump blood throughout the body. In skeletal muscle the contractions enable breathing, movement, and posture maintenance. [1] Contractions in cardiac muscle tissue are due to a myogenic response of the heart's pacemaker cells ...
The trabeculae carneae (columnae carneae or meaty ridges) are rounded or irregular muscular columns which project from the inner surface of the right and left ventricle of the heart. [1] These are different from the pectinate muscles, which are present in the atria of the heart. In development, trabeculae carneae are among the first of the ...
C2C12 myotubes under light microscope, 10x magnification. C2C12 is an immortalized mouse myoblast cell line.The C2C12 cell line is a subclone of myoblasts that were originally obtained by Yaffe and Saxel at the Weizmann Institute of Science in Israel in 1977. [1]
T-tubules (transverse tubules) are extensions of the cell membrane that penetrate into the center of skeletal and cardiac muscle cells.With membranes that contain large concentrations of ion channels, transporters, and pumps, T-tubules permit rapid transmission of the action potential into the cell, and also play an important role in regulating cellular calcium concentration.
It requires cutting out a piece of cardiac muscle to look at the sarcomeres under a microscope. It is currently not possible to directly measure preload in the beating heart of a living animal. Preload is estimated from end-diastolic ventricular pressure and is measured in millimeters of mercury (mmHg).
All cardiac muscle cells are electrically linked to one another, by intercalated discs which allow the action potential to pass from one cell to the next. [1] [2] This means that all atrial cells can contract together, and then all ventricular cells. Different shapes of the cardiac action potential in various parts of the heart