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Diabetic retinopathy (also known as diabetic eye disease) is a medical condition in which damage occurs to the retina due to diabetes.It is a leading cause of blindness in developed countries and one of the lead causes of sight loss in the world, even though there are many new therapies and improved treatments for helping people live with diabetes.
Insulin resistance, or low insulin sensitivity, happens when cells throughout the body don’t respond properly to the hormone insulin, especially cells in muscles, fat and the liver.
Intraretinal microvascular abnormalities (IRMA) are abnormalities of the blood vessels that supply the retina of the eye, a sign of diabetic retinopathy. [1] IRMA can be difficult to distinguish from and is likely a precursor to retinal neovascularization. One way to distinguish IRMA from retinal neovascularization is to perform fluorescein ...
In the early days of insulin treatment for type 1 diabetes there was much debate as to whether strict control of hyperglycaemia would delay or prevent the long-term complications of diabetes. The work of Pirart [ 50 ] suggested that microvascular complications of diabetes were less likely to occur in individuals with better glycaemic control.
Low quality evidence supports the use of anti-VEGF antibodies, such as bevacizumab or pegaptanib which seems to improve outcomes when used in conjunction with laser therapy to treat retinopathy of prematurity, longer term systemic effects are not known however. [25] The evidence is poorer for treatment of diabetic retinopathy.
The causes of macular edema are numerous and different causes may be inter-related. It is commonly associated with diabetes.Chronic or uncontrolled diabetes type 2 can affect peripheral blood vessels including those of the retina which may leak fluid, blood and occasionally fats into the retina causing it to swell.
In 1949, he performed the first successful treatment of a retinal detachment with a light beam (light coagulation) using a self-constructed device on the roof of the ophthalmic clinic at the University of Hamburg-Eppendorf. [13] [14] Results of using laser coagulation to treat diabetic retinopathy were first published in 1954.
Diabetic angiopathy is a form of angiopathy associated with diabetic complications. [1] While not exclusive, the two most common forms are diabetic retinopathy and diabetic nephropathy, whose pathophysiologies are largely identical. Other forms of diabetic angiopathy include diabetic neuropathy and diabetic cardiomyopathy. [2] [3]
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