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Mephentermine, sold under the brand name Wyamine among others, is a sympathomimetic medication which was previously used in the treatment of low blood pressure but is mostly no longer marketed. [ 6 ] [ 5 ] [ 4 ] [ 7 ] [ 8 ] It is used by injection into a vein or muscle , by inhalation , and by mouth .
Phentermine is an norepinephrine and dopamine releasing agent (NDRA) and produces stimulant, rewarding, and appetite suppressant effects. [8] [9] [10] Chemically, it is a substituted amphetamine. [11] Phentermine was approved for medical use in the United States in 1959. [3] It is available as a generic medication. [3]
Phentermine and topiramate was developed by Vivus, a California pharmaceutical company. In December 2009, Vivus, Inc. submitted a new drug application (NDA) to the FDA and on 1 March 2010, Vivus, Inc. announced that the FDA accepted the NDA for review.
In 2023, more than five million Americans 12 and older reported a "prescription use disorder" within the past year, according to the Centers for Disease Control and Prevention (CDC).
Vertex Pharmaceuticals claimed in a press release that the medication can be used for many types of moderate-to-severe acute pain and has shown no evidence that it is addictive, like opioids.
Phentermine is a substituted amphetamine and topiramate has an unknown mechanism of action Approved for weight management (short-term) by the FDA but not the European Medicines Agency [ 54 ] 10% [ 55 ] or 8.25 kilograms (18.2 lb) [ 56 ]
Medical weight management is one of the most popular treatments offered, as many insurance companies do not cover medical weight-loss treatments. "You know it's become very popular with ...
Chlorphentermine, sold under the brand names Apsedon, Desopimon, and Lucofen, is a serotonergic appetite suppressant of the amphetamine family. Developed in 1962, it is the para-chloro derivative of the better-known appetite suppressant phentermine, which is still in current use.
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