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An ethylene oxide sterilized medical device must be sealed in a carefully designed gas-permeable package that enables the ethylene oxide gas to enter.
The four essential parameters (operational ranges) are: gas concentration (450 to 1200 mg/l); temperature (37 to 63°C); relative humidity (40 to 80%) (water molecules carry ETO to reactive sites); and exposure time (1 to 6 hours).
Ethylene Oxide (EtO) gas is one of the most common ways to sterilize medical devices, a safe, tightly controlled, highly regulated process which is critical for preventing infections and ensuring patients have safe surgeries and medical treatments.
STERIS AST’s Ethylene Oxide sterilization uses a 3-part gas process that includes pre-conditioning, sterilization, and aeration. Learn more about EO sterilization here.
Despite its efficacy, recent concerns over environmental and user safety have cast a spotlight on EtO sterilization. This guide offers a deep dive into EtO sterilization, unraveling its processes, advantages, and the critical considerations it demands.
Ethylene oxide (EtO) sterilization is a widely used method in hospitals in the United States. This method involves using ethylene oxide gas to kill all microorganisms on equipment and supplies. EtO is highly effective at sterilizing a wide range of materials, making it a popular choice in healthcare settings. ...
The Crucial Role of Ethylene Oxide in Medical Device Sterilization. Ethylene oxide (EtO) continues to be a critical method for sterilizing medical devices. Its unique compatibility with a broad range of materials and ability to penetrate complex geometries ensures optimal sterility. At C.G. Laboratories, we remain committed to providing high ...
A typical EO sterilization process consists of three phases: preconditioning, sterilization, and aeration. The preconditioning phase of the process consists of subjecting product to controlled temperature and relative humidity conditions for a defined duration.
Ethylene oxide (ETO) has been widely used as a low-temperature sterilant since the 1950s. It has been the most commonly used process for sterilizing temperature- and moisture-sensitive medical devices and supplies in healthcare institutions in the United States.
The most informative epidemiological investigation of ethylene oxide and cancer risk was a study by the National Institute for Occupational Safety and Health (NIOSH) of more than 18,000 employees at 14 commercial sterilization plants where ethylene oxide was used to sterilize medical supplies or food spices (Steenland et al., 2004).