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  2. Mayo Collaborative Services v. Prometheus Laboratories, Inc.

    en.wikipedia.org/wiki/Mayo_Collaborative...

    Mayo v. Prometheus, 566 U.S. 66 (2012), was a case decided by the Supreme Court of the United States that unanimously held that claims directed to a method of giving a drug to a patient, measuring metabolites of that drug, and with a known threshold for efficacy in mind, deciding whether to increase or decrease the dosage of the drug, were not patent-eligible subject matter.

  3. List of antineoplastic agents - Wikipedia

    en.wikipedia.org/wiki/List_of_antineoplastic_agents

    Non-small cell lung cancer, oesophageal cancer, uterine cervical cancer, head and neck cancer and urothelial cancer: Nephrotoxicity, myelosuppression and nausea and vomiting (30-90%). Oxaliplatin: IV: Reacts with DNA, inducing apoptosis, non-cell cycle specific. Colorectal cancer, oesophageal cancer and gastric cancer

  4. Bi-specific T-cell engager - Wikipedia

    en.wikipedia.org/wiki/Bi-specific_T-cell_engager

    A BiTE linking a T cell to a tumor cell. Like other bispecific antibodies, and unlike ordinary monoclonal antibodies, BiTEs form a link between T cells and tumor cells. This causes T cells to exert cytotoxic activity on tumor cells by producing proteins like perforin and granzymes, independently of the presence of MHC I or co-stimulatory molecules.

  5. Ariosa v. Sequenom - Wikipedia

    en.wikipedia.org/wiki/Ariosa_v._Sequenom

    Ariosa Diagnostics, Inc. v. Sequenom, Inc., 788 F.3d 1371 (Fed. Cir. 2015), [1] is a controversial decision of the US Federal Circuit in which the court applied the Mayo v. . Prometheus test [2] to invalidate on the basis of subject matter eligibility a patent said to "solve ... a very practical problem accessing fetal DNA without creating a major health risk for the unborn chil

  6. Association for Molecular Pathology v. Myriad Genetics, Inc.

    en.wikipedia.org/wiki/Association_for_Molecular...

    Association for Molecular Pathology v. Myriad Genetics, Inc., 569 U.S. 576 (2013), was a Supreme Court case, which decided that "a naturally occurring DNA segment is a product of nature and not patent eligible merely because it has been isolated.” [1] However, as a "bizarre conciliatory prize" the Court allowed patenting of complementary DNA, which contains exactly the same protein-coding ...

  7. Proton therapy - Wikipedia

    en.wikipedia.org/wiki/Proton_therapy

    In medicine, proton therapy, or proton radiotherapy, is a type of particle therapy that uses a beam of protons to irradiate diseased tissue, most often to treat cancer.The chief advantage of proton therapy over other types of external beam radiotherapy is that the dose of protons is deposited over a narrow range of depth; hence in minimal entry, exit, or scattered radiation dose to healthy ...

  8. 3-Aminopyridine-2-carboxaldehyde thiosemicarbazone - Wikipedia

    en.wikipedia.org/wiki/3-Aminopyridine-2...

    Vion Pharmaceuticals has also filed several use patents concerning the antiviral and antifungal activity of 3AP. 3AP was initially developed by Vion Pharmaceuticals until company declared bankruptcy in December 2009. Nanotherapeutics, Inc. acquired the product from bankruptcy in 2010 and supported trials at NCI until 2018 when the product was ...

  9. Mayo Foundation for Medical Education & Research v. United ...

    en.wikipedia.org/wiki/Mayo_Foundation_for_Medical...

    Mayo Foundation v. United States , 562 U.S. 44 (2011), is a United States Supreme Court case in which the Court upheld a Treasury Department regulation on the grounds that the courts should defer to government agencies in tax cases in absence of an unreasonable decision on the part of the agency.