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The results of the blood test are then combined with the NT ultrasound measurements, maternal age, and gestational age of the fetus to yield a risk score for Down syndrome, trisomy 18, and trisomy 13. First Trimester Combined Test has a sensitivity (i.e. detection rate for abnormalities) of 82–87% and a false-positive rate of around 5%. [73] [74]
Besides placenta previa and placental abruption, uterine rupture can occur, which is a very serious condition leading to internal or external bleeding. Bleeding from the fetus is rare, but may occur with two conditions called vasa previa and velamentous umbilical cord insertion where the fetal blood vessels lie near the placental insertion site unprotected by Wharton's jelly of the cord. [11]
Hyperemesis gravidarum, which is a severe form of nausea and vomiting of pregnancy can lead to nutritional deficiencies, weight loss, electrolytes imbalance and is one of the leading causes of hospitalization in the first trimester of pregnancy. [36] Constipation is another GI symptom that is commonly encountered during pregnancy. It is ...
Constipation during pregnancy is thought to be due to decreased smooth muscle motility in the bowel caused by normal increases in progesterone. [30] Treatment for constipation includes dietary modifications, including increased fiber and fluid intake, stool softeners, and laxatives. [29]
Chorionic hematoma is the pooling of blood between the chorion, a membrane surrounding the embryo, and the uterine wall. [2] It occurs in about 3.1% of all pregnancies , [ 2 ] it is the most common sonographic abnormality and the most common cause of first trimester bleeding .
CVS usually takes place at 10–12 weeks' gestation, earlier than amniocentesis or percutaneous umbilical cord blood sampling. It is the preferred technique before 15 weeks. [2] CVS was performed for the first time in Milan by Italian biologist Giuseppe Simoni, scientific director of Biocell Center, in 1983. [3]
A 37-year-old nurse booked a colonoscopy after noticing the symptoms while she was pregnant
Routine tests in the first trimester of pregnancy generally include: Complete blood count; Blood type. Rh-negative antenatal patients should receive RhoGAM at 28 weeks to prevent Rh disease. Indirect Coombs test (AGT) to assess risk of hemolytic disease of the newborn [5] Rapid plasma reagin test to screen for syphilis; Rubella antibody screen [6]
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