Search results
Results from the WOW.Com Content Network
Conbercept is a soluble receptor decoy that binds specifically to VEGF-B, placental growth factor (PlGF), and various isoforms of VEGF-A. [1] [4] [15] Conbercept has a VEGF-R2 kinase insert domain receptor (KDR) Ig-like region 4 (KDRd4) which improves the three-dimensional structure and efficiency of dimer formation, thereby increasing the binding capacity of conbercept to VEGF.
In many cases, myopia will stabilize once the growth process has been completed, but in more severe chronic cases, loss of vision can occur. Degenerative myopia, also known as malignant, pathological, or progressive myopia, is characterized by posterior sclera elongation and thinning (at least 25.5 mm to 26.5 mm) and high refractive errors of ...
Low myopia usually describes myopia between −0.50 and −3.00 diopters. [65] Moderate myopia usually describes myopia between −3.00 and −6.00 diopters. [65] Those with moderate amounts of myopia are more likely to have pigment dispersion syndrome or pigmentary glaucoma. [83] High myopia usually describes myopia of −6.00 or more.
Fuchs spots are caused by regression of choroidal neovascularization. [3] Since it is a medical sign, treatment is given for the actual cause. Photothermal laser ablation, photodynamic therapy, anti-VEGF therapy, or a combination of these are the treatment options of choroidal neovascularization due to pathological myopia.
Layers of the eye, with the choroid labelled. Choroidal neovascularization (CNV) is the creation of new blood vessels in the choroid layer of the eye.Choroidal neovascularization is a common cause of neovascular degenerative maculopathy (i.e. 'wet' macular degeneration) [1] commonly exacerbated by extreme myopia, malignant myopic degeneration, or age-related developments.
Ophthalmic drug administration is the administration of a drug to the eyes, most typically as an eye drop formulation. Topical formulations are used to combat a multitude of diseased states of the eye.
In myopia that is no longer progressing, the crescent may be asymptomatic except for its presence on ocular examination. However, in high-degree myopia, it may extend to the upper and lower borders, or form a complete ring around the optic disc and form a central scotoma. The myopic crescent is commonly seen in pathological axial myopia.
Treatment of the deficiency can be accomplished with a vitamin A or multivitamin supplement or by eating foods rich in vitamin A. Treatment with supplements and/or diet can be successful until the disease progresses as far as corneal ulceration, at which point only an extreme surgery can offer a chance of returning sight.