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Methotrexate pneumonitis is a rare complication of therapy and appears to be reducing in frequency in most recent rheumatoid arthritis treatment trials. [41] In the context of rheumatoid arthritis interstitial lung disease, methotrexate treatment may be associated with a lower incidence of ILD over time. [citation needed]
Conventional DMARDs are known to be the first-line treatment for rheumatoid arthritis. [9] Treatment can be a monotherapy or in combination with other anti-arthritic medications. Common DMARDs include oral methotrexate, leflunomide, or sulfasalazine. Conventional DMARDs have a slow onset of action and can take 2–3 months to exhibit effect. [9]
Agents may be used in combination, however, people may experience greater side effects. [8] [122] Methotrexate is the most important and useful DMARD and is usually the first treatment. [8] [5] [123] A combined approach with methotrexate and biologics improves ACR50, HAQ scores and RA remission rates.
For some types of mild to moderate arthritis, OTC medications can help ease pain. This includes acetaminophen (Tylenol®) and nonsteroidal anti-inflammatory drugs (NSAIDs), like ibuprofen (Advil ...
Understanding joint pain is crucial. "Treatment has to be ... an acute flare-up of joint pain but have significant side effects when used for the long term," Dr. Zarin says. ... for the joint pain ...
Side effects: Side effects are possible with any medication, including topical pain relievers. Ahmad says the most common side effect is skin irritation, which certain ingredients or preservatives ...
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