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The BED (Browser Extensible Data) format is a text file format used to store genomic regions as coordinates and associated annotations. The data are presented in the form of columns separated by spaces or tabs. This format was developed during the Human Genome Project [1] and then adopted by other sequencing
Logo of the Human Genome Project. The Human Genome Project (HGP) was an international scientific research project with the goal of determining the base pairs that make up human DNA, and of identifying, mapping and sequencing all of the genes of the human genome from both a physical and a functional standpoint.
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Although the 'completion' of the human genome project was announced in 2001, [2] there remained hundreds of gaps, with about 5–10% of the total sequence remaining undetermined. The missing genetic information was mostly in repetitive heterochromatic regions and near the centromeres and telomeres , but also some gene-encoding euchromatic ...
BioPerl is an active open source software project supported by the Open Bioinformatics Foundation. The first set of Perl codes of BioPerl was created by Tim Hubbard and Jong Bhak [citation needed] at MRC Centre Cambridge, where the first genome sequencing was carried out by Fred Sanger. MRC Centre was one of the hubs and birthplaces of modern ...
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PDF's emphasis on preserving the visual appearance of documents across different software and hardware platforms poses challenges to the conversion of PDF documents to other file formats and the targeted extraction of information, such as text, images, tables, bibliographic information, and document metadata. Numerous tools and source code ...