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Atipamezole, sold under the brand name Antisedan among others, is a synthetic α 2 adrenergic receptor antagonist used for the reversal of the sedative and analgesic effects of dexmedetomidine and medetomidine in dogs. Its reversal effect works by competing with the sedative for α 2-adrenergic receptors and displacing them.
These drugs, including Oxymorphone, Morphine, Fentanyl, Methadone, Buprenorphine, and Butorphanol, have been highly used in veterinary anesthesia due to their sedative and analgesic properties, despite their side effects. [3] [16] Side effects include respiratory depression, slowing of the digestive tract, and cardiovascular stress.
This level, called moderate sedation/analgesia or conscious sedation, causes a drug induced depression of consciousness during which the patient responds purposefully to verbal commands, either alone or accompanied with light physical stimulation. Breathing tubes are not required for this type of anesthesia. This is twilight anesthesia. [2]
Butorphanol is used for sedation and mild to moderate pain control in dogs and cats. It is not considered adequate pain control in dogs undergoing surgical pain. It is used for operative and accident-related pain in small mammals such as dogs, cats, ferrets, coatis, raccoons, mongooses, various marsupials, some rodents and perhaps some larger ...
In the United States, xylazine was approved by the FDA only for veterinary use as a sedative, analgesic, and muscle relaxant in dogs, cats, horses, elk, fallow deer, mule deer, sika deer, and white-tailed deer. [1] [3] The sedative and analgesic effects of xylazine are related to central nervous system depression. Xylazine's muscle relaxant ...
Related: Benadryl for Dogs: Side Effects of Long-Term Use Signs of Benadryl Overdose in Dogs At normal doses, Benadryl is quite safe, but a survey of over 600 dogs (1) found the following signs of ...
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