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  2. 4 Surprising Uses of Viagra (Including What It Was Really ...

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    Whether you’re a senior in high school or a senior-living resident, you’ve likely heard of Viagra (sildenafil) — the original medication for ED. Most men and women know at least vaguely what ...

  3. How to Get Better Viagra Results in 2025 - AOL

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    According to the Food and Drug Administration (FDA), it usually takes 30 to 60 minutes for Viagra or generic sildenafil to start producing a noticeable improvement in your climax quality.

  4. Your ED Pill Guide: Everything You Need to Know Before ... - AOL

    www.aol.com/ed-pill-guide-everything-know...

    Sildenafil (Viagra), tadalafil (Cialis) and vardenafil (Levitra) typically start working within 30 to 60 minutes, while avanafil (Stendra) works within 15 to 30 minutes. As with most prescription ...

  5. Sildenafil - Wikipedia

    en.wikipedia.org/wiki/Sildenafil

    Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [4] [8] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon. [9] It is unclear if it is effective for treating sexual dysfunction in females. [8]

  6. PDE5 inhibitor - Wikipedia

    en.wikipedia.org/wiki/PDE5_inhibitor

    Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.

  7. Discovery and development of phosphodiesterase 5 inhibitors

    en.wikipedia.org/wiki/Discovery_and_development...

    Sildenafil did not prove effective for coronary heart disease but an interesting side effect was discovered, a penile erection. That side effect soon became the main field of investigation. [23] The inhibitor is highly selective for the PDE5 family. [22] Sildenafil is a prototype of PDE5 inhibitors that Pfizer launched as Viagra.

  8. What Happens If You Take Viagra and You Don't Need It? - AOL

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    If you struggle with ED, drugs like Viagra®, sildenafil, tadalafil, and other FDA-approved medications could help with your performance. But if you’re not prescribed one of these meds, taking ...

  9. 5 Must-Know Tips Before Taking Sildenafil 100mg - AOL

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    For example, in clinical trials of sildenafil, 28 percent of men reported headache (by far the most common side effect) at a dosage of 100mg, compared to just 16 percent of men who used 25mg and ...

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