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GAMLSS assumes the response variable follows an arbitrary parametric distribution, which might be heavy or light-tailed, and positively or negatively skewed. In addition, all the parameters of the distribution – location (e.g., mean), scale (e.g., variance) and shape (skewness and kurtosis) – can be modeled as linear, nonlinear or smooth ...
The independent or explanatory variable (say X) can be split up into classes or segments and linear regression can be performed per segment. Segmented regression with confidence analysis may yield the result that the dependent or response variable (say Y) behaves differently in the various segments. [3]
This is the aim of multiple factor analysis which balances the different issues (i.e. the different groups of variables) within a global analysis and provides, beyond the classical results of factorial analysis (mainly graphics of individuals and of categories), several results (indicators and graphics) specific of the group structure.
Multiple comparisons arise when a statistical analysis involves multiple simultaneous statistical tests, each of which has a potential to produce a "discovery". A stated confidence level generally applies only to each test considered individually, but often it is desirable to have a confidence level for the whole family of simultaneous tests. [ 4 ]
In statistics, a central composite design is an experimental design, useful in response surface methodology, for building a second order (quadratic) model for the response variable without needing to use a complete three-level factorial experiment.
The design matrix has dimension n-by-p, where n is the number of samples observed, and p is the number of variables measured in all samples. [4] [5]In this representation different rows typically represent different repetitions of an experiment, while columns represent different types of data (say, the results from particular probes).
Some extensions of response surface methodology deal with the multiple response problem. Multiple response variables create difficulty because what is optimal for one response may not be optimal for other responses. Other extensions are used to reduce variability in a single response while targeting a specific value, or attaining a near maximum ...
If the response data used to estimate the model contain values that change sign, or if the lowest response value is far from zero (for example, when data are left-truncated), a location parameter, L, may be added to the response so that the expressions for the quantile function and for the median become, respectively: