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Similarly, both dual-specificity MAP kinase phosphatases and MAP-specific tyrosine phosphatases bind to MAP kinases through the same docking site. [34] [35] D-motifs can even be found in certain MAPK pathway regulators and scaffolds (e.g. in the mammalian JIP proteins). [citation needed] Other, less well characterised substrate-binding sites ...
Commercially available laboratory-based chemical imaging systems emerged in the early 1990s (ref. 1-5). In addition to economic factors, such as the need for sophisticated electronics and extremely high-end computers, a significant barrier to commercialization of infrared imaging was that the focal plane array (FPA) needed to read IR images were not readily available as commercial items.
In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment.
In cell biology, a biomarker is a molecule that allows the detection and isolation of a particular cell type (for example, the protein Oct-4 is used as a biomarker to identify embryonic stem cells). [33] In genetics, a biomarker (identified as genetic marker) is a DNA sequence that causes disease or is associated with susceptibility to disease ...
Series of density maps for GroEL: from left to right, 4 Å, 8 Å, 16 Å, and 32 Å resolution.The details are smeared away as the resolution becomes lower. Resolution in the context of structural biology is the ability to distinguish the presence or absence of atoms or groups of atoms in a biomolecular structure.
Brain mapping is a set of neuroscience techniques predicated on the mapping of (biological) quantities or properties onto spatial representations of the (human or non-human) brain resulting in maps. According to the definition established in 2013 by Society for Brain Mapping and Therapeutics (SBMT), brain mapping is specifically defined, in ...
(B) Red dots show the dynamics of the microscale model of Figure 2, shown at intervals of one year, using the same values of , , and , and with no mutations (=). (C) Blue dots show the dynamics of the microscale model with mutations having a standard deviation of σ = 0.006 {\displaystyle \sigma =0.006} .
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