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  2. Osteoarthritis - Wikipedia

    en.wikipedia.org/wiki/Osteoarthritis

    Osteoarthritis commonly affects the hands, feet, spine, and the large weight-bearing joints, such as the hips and knees, although in theory, any joint in the body can be affected. As osteoarthritis progresses, movement patterns (such as gait), are typically affected. [1] Osteoarthritis is the most common cause of a joint effusion of the knee. [15]

  3. Arthritis - Wikipedia

    en.wikipedia.org/wiki/Arthritis

    Arthritis is a term often used to mean any disorder that affects joints. [2] Symptoms generally include joint pain and stiffness. [2] Other symptoms may include redness, warmth, swelling, and decreased range of motion of the affected joints.

  4. Knee arthritis - Wikipedia

    en.wikipedia.org/wiki/Knee_arthritis

    In osteoarthritis, there is a loss of articular hyaluronic acid activity, likely contributing to pain and stiffness associated with the condition. Hyaluronic acid injections are an FDA-approved treatment for osteoarthritis of the knee, and are sometimes also used for other joints. However, the merits of HA injections are still disputed.

  5. Gene therapy for osteoarthritis - Wikipedia

    en.wikipedia.org/.../Gene_therapy_for_osteoarthritis

    Unlike pharmacological treatments which are administered locally or systemically as a series of interventions, gene therapy aims to establish sustained therapeutic effect after a single, local injection. [1] The main risk factors for osteoarthritis are age [2] [3] and body mass index, [4] [3] as such, OA is predominantly considered a disease of ...

  6. Trapeziometacarpal osteoarthritis - Wikipedia

    en.wikipedia.org/wiki/Trapeziometacarpal...

    Trapeziometacarpal osteoarthritis (TMC OA) is, also known as osteoarthritis at the base of the thumb, thumb carpometacarpal osteoarthritis, basilar (or basal) joint arthritis, or as rhizarthrosis. [ 3 ] [ 1 ] [ 2 ] This joint is formed by the trapezium bone of the wrist and the metacarpal bone of the thumb.

  7. Disease-modifying osteoarthritis drug - Wikipedia

    en.wikipedia.org/wiki/Disease-modifying...

    A disease-modifying osteoarthritis drug (DMOAD) is a disease-modifying drug that would inhibit or even reverse the progression of osteoarthritis. [1] Since the main hallmark of osteoarthritis is cartilage loss, a typical DMOAD would prevent the loss of cartilage and potentially regenerate it.

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