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A monoclonal antibody (mAb, more rarely called moAb) is an antibody produced from a cell lineage made by cloning a unique white blood cell. All subsequent antibodies derived this way trace back to a unique parent cell.
The advantage of active monoclonal antibody therapy is the fact that the immune system will produce antibodies long-term, with only a short-term drug administration to induce this response. However, the immune response to certain antigens may be inadequate, especially in the elderly.
Download QR code; Print/export Download as PDF; Printable version; In other projects ... is a fully human monoclonal antibody for the treatment of coagulation, [1] ...
This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been withdrawn from market; consequently, the column Use does not necessarily indicate clinical usage. See the list of FDA-approved therapeutic monoclonal antibodies in the monoclonal antibody therapy page.
Download as PDF; Printable version; In other projects Wikidata item; ... Frexalimab (SAR441344) is a second-generation monoclonal antibody that inhibits CD40 ligand.
Download as PDF; Printable version; In other projects Wikidata item; ... Monalizumab is a monoclonal antibody targeted at NKG2A. [4] It is a checkpoint inhibitor. [5] [6]
Download as PDF; Printable version; In other projects Wikidata item; ... Lirilumab is a human monoclonal antibody designed for the treatment of cancer. [1] [2] ...
Sugemalimab, sold under the brand name Cejemly among others, is a monoclonal antibody used for the treatment of metastatic non-small cell lung cancer (NSCLC) in combination with chemotherapy. [1] It is an antineoplastic monoclonal antibody that potentiates T-cell responses, including anti-tumor responses, through blockade of PD-1 binding to PD ...
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