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894 12444 Ensembl ENSG00000118971 ENSMUSG00000000184 UniProt P30279 P30280 RefSeq (mRNA) NM_001759 NM_009829 RefSeq (protein) NP_001750 NP_033959 Location (UCSC) Chr 12: 4.27 – 4.31 Mb Chr 6: 127.13 – 127.15 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse G1/S-specific cyclin-D2 is a protein that in humans is encoded by the CCND2 gene. Function The protein encoded by this gene ...
Cycle (cyc) is a gene in Drosophila melanogaster that encodes the CYCLE protein (CYC). The Cycle gene ( c yc) is expressed in a variety of cell types in a circadian manner. It is involved in controlling both the sleep-wake cycle and circadian regulation of gene expression by promoting transcription in a negative feedback mechanism.
Cyclin-dependent kinase 1 also known as CDK1 or cell division cycle protein 2 homolog is a highly conserved protein that functions as a serine/threonine protein kinase, and is a key player in cell cycle regulation. [5]
66214 Ensembl ENSG00000102760 ENSMUSG00000022018 UniProt Q9H4X1 Q9DBX1 RefSeq (mRNA) NM_014059 NM_025427 RefSeq (protein) NP_054778 NP_079703 Location (UCSC) Chr 13: 41.46 – 41.47 Mb Chr 14: 79.53 – 79.54 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Regulator of cell cycle RGCC (RGCC) also known as response gene to complement 32 protein (RGC-32) is a protein that in humans is ...
CHEK2 regulates cell cycle progression and spindle assembly during mouse oocyte maturation and early embryo development. [ 13 ] [ 14 ] Although CHEK2 is a down stream effector of the ATM kinase that responds primarily to double-strand breaks it can also be activated by ATR (ataxia-telangiectasia and Rad3 related) kinase that responds primarily ...
The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression.
904 12455 Ensembl ENSG00000129315 ENSMUSG00000011960 UniProt O60563 Q9QWV9 RefSeq (mRNA) NM_001240 NM_001277842 NM_009833 NM_001368702 RefSeq (protein) NP_001231 NP_001264771 NP_033963 NP_001355631 Location (UCSC) Chr 12: 48.69 – 48.72 Mb Chr 15: 98.44 – 98.47 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Cyclin-T1 is a protein that in humans is encoded by the CCNT1 gene ...
The CDK4 gene is located on chromosome 12 in humans. [7] The gene is composed of 4,583 base pairs which together code for the 303 amino acid protein with a molecular mass of 33,730 Da. [7] [8] All CDK proteins, including CDK4, have two lobes: the smaller N-terminal lobe (which contains an inhibitory G-loop), and the C terminal lobe (which contains an activation domain and a T-loop).