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  2. Pomalidomide - Wikipedia

    en.wikipedia.org/wiki/Pomalidomide

    Pomalidomide, sold under the brand names Pomalyst and Imnovid, [7] [8] is an anti-cancer medication used for the treatment of multiple myeloma and AIDS-related Kaposi sarcoma. [7] Pomalidomide was approved for medical use in the United States in February 2013, [10] and in the European Union in August 2013. [8] It is available as a generic ...

  3. Cereblon E3 ligase modulator - Wikipedia

    en.wikipedia.org/wiki/Cereblon_E3_ligase_modulator

    This disrupts the positive feedback loop between the two growth factors, possibly causing both multiple birth defects and anti-myeloma effects. Findings also support the hypothesis that an increase in the expression of cereblon is an essential element of the anti-myeloma effect of both lenalidomide and pomalidomide. [29]

  4. GSK blood cancer drug nearly halves risk of death in late ...

    www.aol.com/news/gsk-blood-cancer-drug-nearly...

    The U.S. FDA in April approved two cell therapies - J&J's Carvykti, and Bristol Myers' Abecma - as earlier lines of treatment in less severe multiple myeloma. Eye-related side effects led to a 9% ...

  5. Pomalyst Takes the Stage - AOL

    www.aol.com/news/2013-02-21-pomalyst-takes-the...

    After years of clinical studies, the Food and Drug Administration approved pomalidomide, now branded as Pomalyst, for treatment of relapsed or refractory multiple myeloma on Feb. 8, 2013.

  6. Isatuximab - Wikipedia

    en.wikipedia.org/wiki/Isatuximab

    Isatuximab, sold under the brand name Sarclisa, is a monoclonal antibody (mAb) medication for the treatment of multiple myeloma. [6] [4]The most common side effects include neutropenia (low levels of neutrophils, a type of white blood cell), infusion reactions, pneumonia (infection of the lungs), upper respiratory tract infection (such as nose and throat infections), diarrhoea and bronchitis ...

  7. Oral Anti-Cancer Therapy Pomalidomide Now Approved by ... - AOL

    www.aol.com/2013/08/09/oral-anti-cancer-therapy...

    Oral Anti-Cancer Therapy Pomalidomide Now Approved by European Commission as Treatment for Patients with Relapsed/Refractory Multiple Myeloma - a Rare Form of Blood Cancer BOUDRY, Switzerland ...

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