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Like many other medical conditions, obesity is the result of an interplay between environmental and genetic factors. [2] [3] Studies have identified variants in several genes that may contribute to weight gain and body fat distribution, although only in a few cases are genes the primary cause of obesity.
The extreme endpoint of this distribution are the so-called 'monogenic' obesities where most of the impact on body weight can be tied to a mutation in a single gene that runs in a single family. The classic example of such a genetic effect is the presence of mutations in the leptin gene. [29]
“This means that if someone with small fat cells does gain weight, it may not raise their risk of conditions such as type 2 diabetes and high blood pressure as much as if they had large fat ...
Other critics suggest that race itself may affect the way obesity presents itself in individuals. In a recent study of 70,000 men and women of African ancestry, researchers found three new common genetic variants. [14] These single-nucleotide polymorphisms (SNPs) are connected to body mass index (BMI) and obesity. Therefore, individuals who ...
That said, your weight does have a direct impact on your health. Which is why measurements like body mass index (BMI) can be useful in determining your risk of developing weight-related health ...
Myostatin-related muscle hypertrophy is a rare genetic condition characterized by reduced body fat and increased skeletal muscle size. [1] Affected individuals have up to twice the usual amount of muscle mass in their bodies, but increases in muscle strength are not usually congruent. [ 2 ]
A lesser-known fact about weight loss is that your body’s needs and metabolism change after losing weight, according to research.To put it into context, a 110-pound person requires much fewer ...
A wide variety of body composition measurement methods exist. The gold standard measurement technique for the 4-compartment model consists of a weight measurement, body density measurement using hydrostatic weighing or air displacement plethysmography, total body water calculation using isotope dilution analysis, and mineral content measurement by dual-energy X-ray absorptiometry (DEXA). [1]