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  2. Charles Janeway - Wikipedia

    en.wikipedia.org/wiki/Charles_Janeway

    Together with Alexander Rudensky, Janeway also characterized how self antigens associate with MHC class II molecules. [6] Janeway is particularly well known as the lead author of Immunobiology, a standard textbook on immunology. Since the 2008 publishing of its seventh edition, it has been renamed as Janeway's Immunobiology in his memory. [7]

  3. Immune tolerance - Wikipedia

    en.wikipedia.org/wiki/Immune_tolerance

    [citation needed] Appropriate reactivity toward certain antigens can also be quieted by induction of tolerance after repeated exposure, or exposure in a certain context. In these cases, there is a differentiation of naïve CD4+ helper T cells into induced Treg cells (iTreg cells) in the peripheral tissue or nearby lymphoid tissue (lymph nodes ...

  4. Immunobiology (journal) - Wikipedia

    en.wikipedia.org/wiki/Immunobiology_(journal)

    Immunobiology is a peer-reviewed medical journal covering immunology, published by Elsevier. It was established in 1908 as the Zeitschrift für Immunitätsforschung and renamed Immunobiology in 1980. According to the Journal Citation Reports, the journal has a 2013 impact factor of 3.180. [1]

  5. T helper cell - Wikipedia

    en.wikipedia.org/wiki/T_helper_cell

    T-cell dependent B-cell activation, showing TH2-cell (left) B-cell (right) and several interaction molecules self-made according to Janeway et al, Immunologie (Berlin, 2002) Following development in the thymus, these cells (termed recent thymic emigrants (RTE)) egress from the thymus and home to secondary lymphoid organs (SLO; spleen and lymph ...

  6. Complement system - Wikipedia

    en.wikipedia.org/wiki/Complement_system

    Scheme of the complement system. The complement system, also known as complement cascade, is a part of the humoral, innate immune system and enhances (complements) the ability of antibodies and phagocytic cells to clear microbes and damaged cells from an organism, promote inflammation, and attack the pathogen's cell membrane. [1]

  7. Immunogenicity - Wikipedia

    en.wikipedia.org/wiki/Immunogenicity

    In: Charles Janeway, Paul Travers, Mark Walport, Mark Shlomchik: Immunobiology. The Immune System in Health and Disease. 6th Edition. Garland Science, New York 2004, ISBN 0-8153-4101-6 , p. 683–684

  8. Syngenic - Wikipedia

    en.wikipedia.org/wiki/Syngenic

    Related terms include: [citation needed] autogeneic, referring to autotransplantation, also termed autograft, (from one part of the body to another in the same person) allogeneic, referring to allotransplantation or an allograft (from other individual of same species). xenogeneic, referring to xenotransplantation or a xenograft (from other ...

  9. Major histocompatibility complex - Wikipedia

    en.wikipedia.org/wiki/Major_histocompatibility...

    [citation needed] The first crystal structure of Class I MHC molecule, human HLA-A2, was published in 1989. [17] The structure revealed that MHC-I molecules are heterodimers. They have a polymorphic heavy α-subunit whose gene occurs inside the MHC locus and small invariant β 2 microglobulin subunit whose gene is usually located outside of it ...