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  2. Niacin/simvastatin - Wikipedia

    en.wikipedia.org/wiki/Niacin/simvastatin

    Niacin/simvastatin (trade name Simcor, by Abbott) is a combination drug consisting of an extended release form of the lipid-lowering drug niacin and the statin drug simvastatin. [1] It is used for the treatment of dyslipidemia. It was approved by the FDA on February 15, 2008. [2]

  3. AIM-HIGH (trial) - Wikipedia

    en.wikipedia.org/wiki/AIM-HIGH_(trial)

    Atherothrombosis Intervention in Metabolic Syndrome with Low HDL/High Triglycerides: Impact on Global Health Outcomes (also known as AIM-HIGH) was a randomized control trial designed to assess the efficacy of niacin (extended-release) added to statin therapy in reducing cardiovascular events in patients with established atherosclerotic cardiovascular disease (ASCVD).

  4. Niacin/lovastatin - Wikipedia

    en.wikipedia.org/wiki/Niacin/lovastatin

    Niacin/lovastatin (trade names Advicor) was a drug combination used for the treatment of dyslipidemia.It was a combination of the lipid-modifying drug/vitamin niacin in extended release form and the statin drug lovastatin (trade name Mevacor).

  5. Statin - Wikipedia

    en.wikipedia.org/wiki/Statin

    High cholesterol levels have been associated with cardiovascular disease. [8] There are various forms of statins, some of which include atorvastatin, fluvastatin, lovastatin, pitavastatin, pravastatin, rosuvastatin, and simvastatin. [9] Combination preparations of a statin and another agent, such as ezetimibe/simvastatin, are also

  6. Niacin - Wikipedia

    en.wikipedia.org/wiki/Niacin

    The combination niacin/lovastatin was approved by the U.S. Food and Drug Administration (FDA) in 2001. [57] The combination niacin/simvastatin was approved by the FDA in 2008. [58] [59] Subsequently, large outcome trials using these niacin and statin therapies were unable to demonstrate incremental benefit of niacin beyond statin therapy alone ...

  7. Fenofibrate - Wikipedia

    en.wikipedia.org/wiki/Fenofibrate

    Fenofibrate (sold under the brand name Tricor among others), is an oral medication of the fibrate class used to treat abnormal blood lipid levels. [3] It is less commonly used compared to statins because it treats a different type of cholesterol abnormality to statins.

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  9. Additive effect - Wikipedia

    en.wikipedia.org/wiki/Additive_effect

    Another drug combination with additive effect for hypercholesterolemia is niacin and simvastatin. This drug combination is also known as Simcor commercially. Niacin can reduce the secretion of LDL cholesterol and very-low-density lipoprotein cholesterol (VLDL cholesterol).

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