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These diverticula make their appearance before the closure of the anterior end of the neural tube; [1] [2] after the closure of the tube around the 4th week of development, they are known as the optic vesicles. Previous studies of optic vesicles suggest that the surrounding extraocular tissues – the surface ectoderm and extraocular mesenchyme ...
The optic vesicles project toward the sides of the head, and the peripheral part of each expands to form a hollow bulb, while the proximal part remains narrow and constitutes the optic stalk. [1] [2] Closure of the choroidal fissure in the optic stalk occurs during the seventh week of development. The former optic stalk is then called the optic ...
The optic vesicles then begin to form the optic cup. [3] [4] Optic cup morphogenesis is the invagination process occurring after neuroectoderm movement forms the spherical optic vesicle (Phase 1). Invagination is when a tissue folds back on itself.
Invagination is the process of folding in cells. The lens placode invaginates to later develop the lens or lens pit. The development of the lens placode is typically seen between 44 and 50 hours; invagination occurs shortly after at around the 50–55-hour mark.
The lens placode under the direction of the optic vesicle gives rise to the lens of the eye. The adenohypophyseal placode , which forms the anterior lobe of the pituitary gland . Other animals
The neural fold is a structure that arises during neurulation in the embryonic development of both birds and mammals among other organisms. [1] [2] This structure is associated with primary neurulation, meaning that it forms by the coming together of tissue layers, rather than a clustering, and subsequent hollowing out, of individual cells (known as secondary neurulation).
Neurulation is a process in vertebrate embryos at the neurula stage in which the neural tube is formed. [ 6 ] [ 8 ] There are two types of neurulation: primary and secondary neurulation . Primary neurulation refers to the formation and inward folding of the neural plate upon itself to form the neural tube.
The optical vesicle (which eventually becomes the optic nerve, retina and iris) forms at the basal plate of the prosencephalon. The alar plate of the prosencephalon expands to form the cerebral hemispheres (the telencephalon) whilst its basal plate becomes the diencephalon. Finally, the optic vesicle grows to form an optic outgrowth.