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Content focuses on all aspects of clinical pharmacology and accepts both original scholarship as well as reviews. The journal has a rigorous peer-review process. The journal publishes most of the time almost instantly upon acceptance with a normal turnaround time of 72 hours. The current commissioning editor is Jermaine Wilcock. [1]
In clinical practice, this means that it takes 4 to 5 times the half-life for a drug's serum concentration to reach steady state after regular dosing is started, stopped, or the dose changed. So, for example, digoxin has a half-life (or t 1 / 2 ) of 24–36 h; this means that a change in the dose will take the best part of a week to ...
Quantitative systems pharmacology (QSP) is a discipline within biomedical research that uses mathematical computer models to characterize biological systems, disease processes and drug pharmacology. [ 1 ] [ 2 ] QSP can be viewed as a sub-discipline of pharmacometrics that focuses on modeling the mechanisms of drug pharmacokinetics (PK ...
Both pharmacology and toxicology are scientific disciplines that focus on understanding the properties and actions of chemicals. [23] However, pharmacology emphasizes the therapeutic effects of chemicals, usually drugs or compounds that could become drugs, whereas toxicology is the study of chemical's adverse effects and risk assessment. [23]
The obvious answer is that all that filler makes for a cheaper product. But the filler also serves a culinary purpose. Real cheese that’s been overheated can separate into oily puddles.
The SS United States may be sunk in the near future, but its memories live on through those who experienced it.. Despite great efforts to revamp the iconic ocean liner, following a lawsuit, the SS ...
Related: Amy Robach Recalls the Moment T.J. Holmes Told Her He Loved Her After Building 'Deep Foundation of Friendship' The broadcaster said it "was a big day for us a year ago," telling the ...
Therapeutic drug monitoring (TDM) is a branch of clinical chemistry and clinical pharmacology that specializes in the measurement of medication levels in blood.Its main focus is on drugs with a narrow therapeutic range, i.e. drugs that can easily be under- or overdosed. [1]
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