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Spondweni virus (SPOV or SPONV) is an arbovirus, or arthropod-borne virus, which is a member of the family Flaviviridae and the genus Flavivirus. [ 1 ] [ 2 ] It is part of the Spondweni serogroup which consists of the Sponweni virus and the Zika virus (ZIKV).
Tissue tropism is the range of cells and tissues of a host that support growth of a particular pathogen, such as a virus, bacterium or parasite. [1] [2] Some bacteria and viruses have a broad tissue tropism and can infect many types of cells and tissues. [1] Other viruses may infect primarily a single tissue. [1]
Influenza B virus is almost exclusively a human pathogen, and is less common than influenza A. The only other animal known to be susceptible to influenza B infection is the seal . [ 47 ] This type of influenza mutates at a rate 2–3 times lower than type A [ 48 ] and consequently is less genetically diverse, with only one influenza B serotype ...
The name of the family, Poxviridae, is a legacy of the original grouping of viruses associated with diseases that produced poxes on the skin.Modern viral classification is based on phenotypic characteristics; morphology, nucleic acid type, mode of replication, host organisms, and the type of disease they cause.
The virus exits the host cell by nuclear egress, and nuclear pore export. Birds and pigs serve as the natural host. [ 9 ] [ 7 ] The virus is known to cause "immunosuppressive conditions" in animals that are infected; as well as having the ability to jump between species, creating difficulty in identifying the origin of infection.
Canine distemper virus is closely related to measles virus and is the most important viral disease of dogs. The disease (which was first described in 1760, by Edward Jenner, the pioneer of smallpox vaccination, is highly contagious, but is well controlled by vaccination. In the 1990s, thousands of African lions died from the infection, which ...
It binds to molecules on the surface of cells called receptors and drives the entry of the virus into the cell. [43] VP4 has to be modified by the protease enzyme trypsin, which is found in the gut, into VP5* and VP8* before the virus is infectious. [44] VP4 determines how virulent the virus is and it determines the P-type of the virus. [45]
Transmissible spongiform encephalopathies (TSEs), also known as prion diseases, [1] are a group of progressive, incurable, and fatal conditions that are associated with the prion hypothesis and affect the brain and nervous system of many animals, including humans, cattle, and sheep.